电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

PDGFB 抗体 (N-Term)

PDGFB 适用: 人, 大鼠, 小鼠, 犬, 绵羊, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2787714
发货至: 中国
  • 抗原 See all PDGFB 抗体
    PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))
    抗原表位
    • 16
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 大鼠, 小鼠, 犬, 绵羊, Cow, 豚鼠
    宿主
    • 52
    • 9
    • 1
    克隆类型
    • 55
    • 7
    多克隆
    标记
    • 29
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDGFB antibody is un-conjugated
    应用范围
    • 55
    • 21
    • 15
    • 13
    • 13
    • 13
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    NRCWALFLSL CCYLRLVSAE GDPIPEELYE MLSDHSIRSF DDLQRLLHGD
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Sheep: 100%
    产品特性
    This is a rabbit polyclonal antibody against PDGFB. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human PDGFB
    Top Product
    Discover our top product PDGFB Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 241 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))
    别名
    PDGFB (PDGFB 产品)
    别名
    PDGF-2 antibody, PDGF2 antibody, SIS antibody, SSV antibody, c-sis antibody, pdgf2 antibody, sis antibody, si:ch211-79m20.1 antibody, si:dkey-261d11.1 antibody, PDGF-B antibody, Sis antibody, platelet derived growth factor subunit B antibody, platelet-derived growth factor beta polypeptide antibody, platelet derived growth factor subunit B S homeolog antibody, platelet-derived growth factor beta polypeptide a antibody, platelet derived growth factor, B polypeptide antibody, PDGFB antibody, pdgfb.S antibody, pdgfba antibody, Pdgfb antibody
    背景
    PDGFB is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor.The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two splice variants have been identified for this gene.
    Alias Symbols: FLJ12858, PDGF2, SIS, SSV, c-sis
    Protein Interaction Partner: COL6A1, COL5A1, COL4A1, COL3A1, COL2A1, COL1A2, COL1A1, LYVE1, NRP1, ADIPOQ, MDFI, PDAP1, ART1, PDGFB, HRAS, THBS1, PDGFRA, PDGFRB, HSPG2, LRP1, A2M, SPARC,
    Protein Size: 241
    分子量
    27 kDa
    基因ID
    5155
    NCBI登录号
    NM_002608, NP_002599
    UniProt
    P01127
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
You are here:
客服