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Calpain S1 抗体 (Middle Region)

CAPNS1 适用: 人, 小鼠, 大鼠, Cow, 兔, Pig, 犬, 豚鼠, 马, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2787678
发货至: 中国
  • 抗原 See all Calpain S1 (CAPNS1) 抗体
    Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))
    抗原表位
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, Cow, 兔, Pig, 犬, 豚鼠, 马, 绵羊
    宿主
    • 28
    • 7
    克隆类型
    • 29
    • 6
    多克隆
    标记
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Calpain S1 antibody is un-conjugated
    应用范围
    • 16
    • 10
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    RRYSDESGNM DFDNFISCLV RLDAMFRAFK SLDKDGTGQI QVNIQEWLQL
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
    产品特性
    This is a rabbit polyclonal antibody against CAPNS1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human CAPNS1
    Top Product
    Discover our top product CAPNS1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 268 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Kulkarni, Liu, Qi, Zhu, Klinke, Liu: "Differential proteomic analysis of caveolin-1 KO cells reveals Sh2b3 and Clec12b as novel interaction partners of caveolin-1 and Capns1 as a potential mediator of caveolin-1-induced apoptosis." in: The Analyst, Vol. 138, Issue 22, pp. 6986-96, (2013) (PubMed).

  • 抗原
    Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))
    别名
    CAPNS1 (CAPNS1 产品)
    别名
    30K antibody, CALPAIN4 antibody, CANP antibody, CANPS antibody, CAPN4 antibody, CDPS antibody, CSS1 antibody, Capn4 antibody, CAPNS1 antibody, Capa-4 antibody, Capa4 antibody, D7Ertd146e antibody, MGC84330 antibody, capns1 antibody, cb616 antibody, wu:fb81g08 antibody, wu:fl09e04 antibody, zgc:110603 antibody, calpain small subunit 1 antibody, calpain, small subunit 1 antibody, calpain, small subunit 1 L homeolog antibody, calpain, small subunit 1 a antibody, CAPNS1 antibody, Capns1 antibody, capns1.L antibody, capns1a antibody
    背景
    Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.
    Alias Symbols: 30K, CALPAIN4, CANP, CANPS, CAPN4, CDPS, CSS1
    Protein Interaction Partner: AGTRAP, HUWE1, NEDD1, TUBGCP2, TUBGCP3, CDC20, UBC, OGFOD1, STK26, ISOC1, DCPS, MAT2B, PROSC, FERMT2, YWHAQ, PDIA4, YWHAZ, YWHAH, YWHAG, YWHAE, PTMA, PPP1CA, PAK2, PAFAH1B1, MYO1E, MAT2A, GNAI3, GAPDH, EIF5, TBCB, ALDH7A1, ASNS, APEX1, ADRB2, PPARGC1A, VC
    Protein Size: 268
    分子量
    29 kDa
    基因ID
    826
    NCBI登录号
    NM_001003962, NP_001003962
    UniProt
    P04632
    途径
    Apoptosis
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