Calpain S1 抗体 (Middle Region)
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北京 101111
Quick Overview for Calpain S1 抗体 (Middle Region) (ABIN2787678)
抗原
See all Calpain S1 (CAPNS1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- RRYSDESGNM DFDNFISCLV RLDAMFRAFK SLDKDGTGQI QVNIQEWLQL
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
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产品特性
- This is a rabbit polyclonal antibody against CAPNS1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CAPNS1
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anti-Calpain, Small Subunit 1 (CAPNS1) (AA 172-260) antibody
CAPNS1 适用: 人 WB, ELISA, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3C4 unconjugated
anti-Calpain, Small Subunit 1 (CAPNS1) (AA 1-268) antibodyCAPNS1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Calpain, Small Subunit 1 (CAPNS1) (AA 69-268) antibodyCAPNS1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calpain, Small Subunit 1 (CAPNS1) (AA 69-268) antibodyCAPNS1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calpain, Small Subunit 1 (CAPNS1) antibodyCAPNS1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calpain, Small Subunit 1 (CAPNS1) (AA 84-268) antibodyCAPNS1 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal AT1D11 unconjugated
anti-Calpain, Small Subunit 1 (CAPNS1) (Internal Region) antibodyCAPNS1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calpain, Small Subunit 1 (CAPNS1) (AA 1-268) antibodyCAPNS1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Calpain, Small Subunit 1 (CAPNS1) (AA 1-268) antibodyCAPNS1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Calpain, Small Subunit 1 (CAPNS1) antibodyCAPNS1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 268 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Differential proteomic analysis of caveolin-1 KO cells reveals Sh2b3 and Clec12b as novel interaction partners of caveolin-1 and Capns1 as a potential mediator of caveolin-1-induced apoptosis." in: The Analyst, Vol. 138, Issue 22, pp. 6986-96, (2013) (PubMed).
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: "Differential proteomic analysis of caveolin-1 KO cells reveals Sh2b3 and Clec12b as novel interaction partners of caveolin-1 and Capns1 as a potential mediator of caveolin-1-induced apoptosis." in: The Analyst, Vol. 138, Issue 22, pp. 6986-96, (2013) (PubMed).
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- Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))
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别名
- CAPNS1
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背景
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Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: 30K, CALPAIN4, CANP, CANPS, CAPN4, CDPS, CSS1
Protein Interaction Partner: AGTRAP, HUWE1, NEDD1, TUBGCP2, TUBGCP3, CDC20, UBC, OGFOD1, STK26, ISOC1, DCPS, MAT2B, PROSC, FERMT2, YWHAQ, PDIA4, YWHAZ, YWHAH, YWHAG, YWHAE, PTMA, PPP1CA, PAK2, PAFAH1B1, MYO1E, MAT2A, GNAI3, GAPDH, EIF5, TBCB, ALDH7A1, ASNS, APEX1, ADRB2, PPARGC1A, VC
Protein Size: 268 -
分子量
- 29 kDa
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基因ID
- 826
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NCBI登录号
- NM_001003962, NP_001003962
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UniProt
- P04632
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途径
- Apoptosis
抗原
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