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CCR2 抗体 (C-Term)

There are 2+ publications for this product available. The 兔 多克隆 anti-CCR2 antibody is suitable to detect CCR2 in samples from 人, 犬, Cow 和 马. It has been validated for WB.
产品编号 ABIN2787667
发货至: 中国
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Quick Overview for CCR2 抗体 (C-Term) (ABIN2787667)

抗原

See all CCR2 抗体
CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

适用

  • 117
  • 60
  • 41
  • 12
  • 2
  • 1
  • 1
人, 犬, Cow, 马

宿主

  • 99
  • 20
  • 4
  • 1
  • 1

克隆类型

  • 83
  • 39
  • 2
多克隆

标记

  • 51
  • 8
  • 7
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
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  • 2
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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
This CCR2 antibody is un-conjugated

应用范围

  • 47
  • 45
  • 32
  • 27
  • 14
  • 12
  • 11
  • 7
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 16
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    FTIMIVYFLF WTPYNIVILL NTFQEFFGLS NCESTSQLDQ ATQVTETLGM

    预测反应

    Cow: 79%, Dog: 79%, Horse: 79%, Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against CCR2. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 374 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Toka, Dunaway, Smaltz, Szulc-Dąbrowska, Drnevich, Mielcarska, Bossowska-Nowicka, Schweizer: "Bacterial and viral pathogen-associated molecular patterns induce divergent early transcriptomic landscapes in a bovine macrophage cell line." in: BMC genomics, Vol. 20, Issue 1, pp. 15, (2019) (PubMed).

    Murakami, Maeda, Yonezawa, Matsuki: "CC chemokine ligand 2 and CXC chemokine ligand 8 as neutrophil chemoattractant factors in canine idiopathic polyarthritis." in: Veterinary immunology and immunopathology, Vol. 182, pp. 52-58, (2016) (PubMed).

  • 抗原

    CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

    别名

    CCR2

    背景

    This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase.
    Alias Symbols: CKR2, CCR-2, CCR2A, CCR2B, CD192, CKR2A, CKR2B, CMKBR2, MCP-1-R, CC-CKR-2
    Protein Size: 374

    分子量

    42 kDa

    基因ID

    1231

    NCBI登录号

    NM_000647, NP_000638

    UniProt

    P41597

    途径

    cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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