CCR2 抗体 (Middle Region)
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北京 101111
Quick Overview for CCR2 抗体 (Middle Region) (ABIN2787666)
抗原
See all CCR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- LIMVICYSGI LKTLLRCRNE KKRHRAVRVI FTIMIVYFLF WTPYNIVILL
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预测反应
- Human: 100%, Pig: 93%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against CKR-2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CCR2
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anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody
CCR2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3B6B1 unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 19-32), (Extracellular) antibodyCCR2 适用: 小鼠 WB, FACS, IHC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 301-373) antibodyCCR2 适用: 人, 小鼠, 大鼠 ELISA, FACS, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibodyCCR2 适用: 人, 小鼠, 大鼠, 犬 IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) (N-Term) antibodyCCR2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibodyCCR2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) (N-Term) antibodyCCR2 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-42) antibodyCCR2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D12 unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibodyCCR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody (HRP)CCR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal HRP
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 374 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "A novel network pharmacology approach to analyse traditional herbal formulae: the Liu-Wei-Di-Huang pill as a case study." in: Molecular bioSystems, Vol. 10, Issue 5, pp. 1014-22, (2014) (PubMed).
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: "A novel network pharmacology approach to analyse traditional herbal formulae: the Liu-Wei-Di-Huang pill as a case study." in: Molecular bioSystems, Vol. 10, Issue 5, pp. 1014-22, (2014) (PubMed).
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- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
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别名
- CCR2
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背景
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This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase.This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
Alias Symbols: CC-CKR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R
Protein Size: 374 -
分子量
- 42 kDa
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基因ID
- 1231
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NCBI登录号
- NM_000647, NP_000638
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UniProt
- P41597
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途径
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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