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H2AFX 抗体 (N-Term)

Name: H2AFX 抗体 (N-Term)
SKU: ABIN2787619
Availability: OutOfStock

This anti-H2AFX antibody is a 兔多克隆 antibody detecting H2AFX in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 斑马鱼和马. This Primary Antibody has been cited in 1 publication.

WB Suggested Anti-H2AFX Antibody Titration: 0. (H2AFX 抗体 (N-Term))

1 image

(1 reference)

产品编号 ABIN2787619

发货至: 中国

Quick Overview for H2AFX 抗体 (N-Term) (ABIN2787619)

抗原

See all H2AFX 抗体

H2AFX (H2A Histone Family, Member X (H2AFX))

适用

人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 斑马鱼, 马

宿主

兔

克隆类型

多克隆

标记

This H2AFX antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product H2AFX Primary Antibody

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N-Term

序列

SGRGKTGGKA RAKAKSRSSR AGLQFPVGRV HRLLRKGHYA ERVGAGAPVY

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

产品特性

This is a rabbit polyclonal antibody against H2AFX. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human H2AFX
anti-H2A Histone Family, Member X (H2AFX) (AA 115-143), (C-Term) antibody
H2AFX 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 938CT5-1-1 unconjugated

anti-H2A Histone Family, Member X (H2AFX) (pSer140) antibody
H2AFX 适用: 人 WB, ELISA, IHC (p), ICC, FACS, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (ubLys119) antibody
H2AFX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) antibody
H2AFX 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 8C5 unconjugated

anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibody
H2AFX 适用: 人 WB, ELISA, IF, ChIP 宿主: 兔 Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibody
H2AFX 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibody
H2AFX 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (C-Term) antibody
H2AFX 适用: 人 WB, IF, ICC, ChIP 宿主: 兔 Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (pTyr143) antibody
H2AFX 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), ICC, FACS, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibody
H2AFX 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Monoclonal 1C14 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 143 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Wen, Zhu, Zhang, Keum, Zykova, Yao, Peng, Zheng, Cho, Ma, Bode, Dong: "MST1 promotes apoptosis through phosphorylation of histone H2AX." in: The Journal of biological chemistry, Vol. 285, Issue 50, pp. 39108-16, (2010) (PubMed).
抗原

H2AFX (H2A Histone Family, Member X (H2AFX))

别名

H2AFX

背景

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. H2AFX is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: H2A.X, H2A/X, H2AX
Protein Interaction Partner: UBC, HIST1H3A, USP17L2, UBD, RNF8, DDX21, XRCC6, NBN, NCL, HIST1H3B, ESR1, CENPA, TP53BP1, TOPORS, MDC1, BRCA1, ATR, ATM, PRKDC, CBX5, TRIM28, EGFR, BMI1, HIST2H3C, PML, XRCC5, UBB, TERF2, RNF2, SIRT7, CSNK2A1, ARRB2, ARRB1, PAXIP1, MRE11A, ATF2, MCPH1, C
Protein Size: 143

分子量

16 kDa

基因ID

3014

NCBI登录号

NM_002105, NP_002096

UniProt

P16104

途径

Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus