CEBPB 抗体 (N-Term)
Quick Overview for CEBPB 抗体 (N-Term) (ABIN2787467)
抗原
See all CEBPB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- AIDFSPYLEP LGAPQAPAPA TATDTFEAAP PAPAPAPASS GQHHDFLSDL
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预测反应
- Cow: 86%, Dog: 92%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against CEBPB. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CEBPB
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 345 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))
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别名
- CEBPB
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背景
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CEBPB is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: C/EBP-beta, CRP2, IL6DBP, LAP, MGC32080, NF-IL6, TCF5
Protein Interaction Partner: CEBPA, UBC, EGR1, EP300, TP63, RB1, RELA, DAXX, CASP8, CASP1, SMARCA2, HDAC1, SMARCC1, SMARCB1, SMARCA4, SMARCA5, TAF9, ELAVL1, SUMO2, TRIM28, CEBPB, ATF3, CARM1, GSK3B, SUMO1, KAT2A, HDAC9, KAT2B, NCOR2, NCOR1, STAT3, PPARG, NRF1, CREBBP, ATF2, EHMT2, SP
Protein Size: 345 -
分子量
- 36 kDa
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基因ID
- 1051
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NCBI登录号
- NM_005194, NP_005185
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UniProt
- P17676
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途径
- Interferon-gamma Pathway, Autophagy, Brown Fat Cell Differentiation
抗原
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