TCF7L1 抗体 (N-Term)
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北京 101111
Quick Overview for TCF7L1 抗体 (N-Term) (ABIN2787453)
抗原
See all TCF7L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- TCF7L1 Antibody - N-terminal region
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序列
- ESENQSSSSD SEAERRPQPV RDTFQKPRDY FAEVRRPQDS AFFKGPPYPG
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预测反应
- Cow: 86%, Dog: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against TCF7L1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TCF7L1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57917-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))
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别名
- TCF7L1
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背景
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Background Information: TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.
Gene Name: Transcription factor 7-like 1 (T-cell specific, HMG-box)
Alternative Symbols: TCF3, TCF-3
Protein Name: Transcription factor 7-like 1
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分子量
- 63kDa
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基因ID
- 83439
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NCBI登录号
- NP_112573
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UniProt
- Q9HCS4
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途径
- WNT signaling, Stem Cell Maintenance
抗原
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