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PIDD 抗体 (N-Term)

The 兔 多克隆 anti-PIDD antibody (ABIN2787143) specifically detects PIDD in WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN2787143
发货至: 中国
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Quick Overview for PIDD 抗体 (N-Term) (ABIN2787143)

抗原

See all PIDD 抗体
PIDD (P53-Induced Death Domain Protein (PIDD))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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多克隆

标记

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This PIDD antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    原理

    PIDD1 Antibody - N-terminal region

    序列

    RLQGNPLGEA SPDAPSSPVA ALIPEMPRLF LTSDLDSFPV TPQGCSVTLA

    预测反应

    Human: 100%, Mouse: 86%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against LRDD. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human LRDD
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57269-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PIDD (P53-Induced Death Domain Protein (PIDD))

    别名

    PIDD1

    背景

    Background Information: The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.

    Gene Name: p53-induced death domain protein 1

    Alternative Symbols: LRDD, PIDD

    Protein Name: p53-induced death domain-containing protein 1

    分子量

    83kDa

    基因ID

    55367

    NCBI登录号

    NP_060964

    UniProt

    Q9HB75

    途径

    p53 Pathway, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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