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PEX5 抗体 (Middle Region)

This anti-PEX5 antibody is a 兔 多克隆 antibody detecting PEX5 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠, Cow 和 Pig.
产品编号 ABIN2786513
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PEX5 抗体 (Middle Region) (ABIN2786513)

抗原

See all PEX5 抗体
PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))

适用

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人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠, Cow, Pig

宿主

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克隆类型

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多克隆

标记

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This PEX5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    序列

    LNMQRKSRGP RGEGGAMSEN IWSTLRLALS MLGQSDAYGA ADARDLSTLL

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against PEX5. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human PEX5
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 631 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))

    别名

    PEX5

    背景

    PEX5 binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD).
    Alias Symbols: PTS1R, PXR1, PTS1-BP
    Protein Interaction Partner: CAPRIN2, CCDC14, TOMM7, PRR13, GDPD5, ZNF772, EP400NL, TM6SF1, ACOT8, RPL14, MKRN3, S100A6, LDHB, RANBP6, GSTK1, ZADH2, TYSND1, HSDL2, ACAD11, LONP2, PECR, HSD17B4, HOXA7, EHHADH, ECH1, CRAT, CAT, BRCA1, ACOX1, DECR2, HACL1, DHRS4, ECI2, AGPS, GNPAT, UBC,
    Protein Size: 631

    分子量

    70 kDa

    基因ID

    5830

    NCBI登录号

    NM_000319, NP_000310

    途径

    Monocarboxylic Acid Catabolic Process
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