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DAAM1 抗体 (Middle Region)

DAAM1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 斑马鱼, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2786070
发货至: 中国
  • 抗原 See all DAAM1 抗体
    DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
    抗原表位
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 46
    • 11
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 斑马鱼, 犬
    宿主
    • 42
    • 4
    克隆类型
    • 43
    • 3
    多克隆
    标记
    • 24
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DAAM1 antibody is un-conjugated
    应用范围
    • 39
    • 31
    • 27
    • 9
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    GNTVQYWLLL DRIIQQIVIQ NDKGQDPDST PLENFNIKNV VRMLVNENEV
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    产品特性
    This is a rabbit polyclonal antibody against DAAM1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human DAAM1
    Top Product
    Discover our top product DAAM1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1078 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
    别名
    DAAM1 (DAAM1 产品)
    背景
    Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein.Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.
    Alias Symbols: FLJ41657, KIAA0666
    Protein Interaction Partner: UBC, PRPF40A, B3GALT4, AMBP, MAP3K7, DVL2, DVL1, RHOA,
    Protein Size: 1078
    分子量
    123 kDa
    基因ID
    23002
    NCBI登录号
    NM_014992, NP_055807
    UniProt
    Q9Y4D1
    途径
    WNT signaling
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