Ubiquilin 1 抗体 (Middle Region)
Quick Overview for Ubiquilin 1 抗体 (Middle Region) (ABIN2785977)
抗原
See all Ubiquilin 1 (UBQLN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- QFGGNPFASL VSNTSSGEGS QPSRTENRDP LPNPWAPQTS QSSSASSGTA
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against UBQLN1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human UBQLN1
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anti-Ubiquilin 1 (UBQLN1) (AA 290-339) antibody
UBQLN1 适用: 人, Cow, 犬, 豚鼠, 马, 兔, 绵羊, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 1 (UBQLN1) (AA 296-326) antibodyUBQLN1 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 1 (UBQLN1) (AA 1-300) antibodyUBQLN1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 1 (UBQLN1) (AA 1-589) antibodyUBQLN1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C6-A3 unconjugated
anti-Ubiquilin 1 (UBQLN1) (AA 1-589) antibodyUBQLN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C6-B7 unconjugated
anti-Ubiquilin 1 (UBQLN1) (Internal Region) antibodyUBQLN1 适用: 人 WB, ELISA, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal 3D5E2 unconjugated
anti-Ubiquilin 1 (UBQLN1) (AA 296-326) antibodyUBQLN1 适用: 人, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB4554 unconjugated
anti-Ubiquilin 1 (UBQLN1) antibodyUBQLN1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 1 (UBQLN1) (AA 19-49), (N-Term) antibodyUBQLN1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB4615 unconjugated
anti-Ubiquilin 1 (UBQLN1) (AA 40-70) antibodyUBQLN1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 589 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Ubiquilin 1 (UBQLN1)
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别名
- UBQLN1
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背景
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UBQLN1 is an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DA41, DSK2, FLJ90054, PLIC-1, XDRP1, UBQN
Protein Interaction Partner: MLLT6, MCM7, IL6ST, IGLC1, IGL, SLC29A2, HK2, GYPB, GRM2, GPX3, GABRD, FN1, FKBP2, FCGR2A, DEFA6, CTAG1B, CSTF2, COL10A1, COL1A2, CALU, IGLV2-14, FAM127B, CSTF2T, FAM127C, TMEM31, AGR3, ITPRIPL1, TRIM32, ACOT7, PLA2G16, SMR3B, AGR2, PSMD6, NUPL1, IST1, LI
Protein Size: 589 -
分子量
- 62 kDa
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基因ID
- 29979
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NCBI登录号
- NM_013438, NP_038466
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UniProt
- Q5T6J9
抗原
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