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14-3-3 sigma/SFN 抗体 (N-Term)

This anti-14-3-3 sigma/SFN antibody is a 兔 多克隆 antibody detecting 14-3-3 sigma/SFN in WB. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 绵羊 和 豚鼠.
产品编号 ABIN2785885
发货至: 中国

Quick Overview for 14-3-3 sigma/SFN 抗体 (N-Term) (ABIN2785885)

抗原

See all 14-3-3 sigma/SFN (SFN) 抗体
14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

适用

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人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 绵羊, 豚鼠

宿主

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克隆类型

  • 89
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多克隆

标记

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This 14-3-3 sigma/SFN antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    VVGGQRAAWR VLSSIEQKSN EEGSEEKGPE VREYREKVET ELQGVCDTVL

    预测反应

    Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%

    产品特性

    This is a rabbit polyclonal antibody against SFN. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human SFN
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 248 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

    别名

    SFN

    背景

    SFN is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. SFN binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, SFN regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.
    Alias Symbols: YWHAS
    Protein Interaction Partner: FAM9B, RAB3IP, LONRF1, CCDC102B, ZC2HC1C, DTL, FAM53C, MKRN3, FOXO4, MAGEA1, CCNH, SIK3, ZFYVE19, YWHAZ, VCL, UBE2V1, SNRPF, UBE2R2, PAK2, G6PD, TARDBP, EGFR, BAD, MARK3, HDAC7, HDAC5, HDAC4, RAF1, CDC25C, MST1R, ABL1, HNRNPD, ATF2, TRIM32, COPS6, UBC, TP
    Protein Size: 248

    分子量

    28 kDa

    基因ID

    2810

    NCBI登录号

    NM_006142, NP_006133

    UniProt

    P31947

    途径

    p53 Pathway, Myometrial Relaxation and Contraction
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