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INHBA 抗体 (N-Term)

Cited in 1 publication. This anti-INHBA antibody is a 兔 多克隆 antibody detecting INHBA in WB. Suitable for 人, 大鼠, 小鼠, Cow, Pig, 马, 绵羊, 山羊, 犬 和 兔.
产品编号 ABIN2785821
发货至: 中国
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Quick Overview for INHBA 抗体 (N-Term) (ABIN2785821)

抗原

See all INHBA 抗体
INHBA (Inhibin, beta A (INHBA))

适用

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人, 大鼠, 小鼠, Cow, Pig, 马, 绵羊, 山羊, 犬, 兔

宿主

  • 83
  • 13

克隆类型

  • 81
  • 16
多克隆

标记

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This INHBA antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    CPSCALAALP KDVPNSQPEM VEAVKKHILN MLHLKKRPDV TQPVPKAALL

    预测反应

    Cow: 100%, Dog: 93%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%

    产品特性

    This is a rabbit polyclonal antibody against INHBA. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human INHBA
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 426 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ndiaye, Castonguay, Benoit, Silversides, Lussier: "Differential regulation of Janus kinase 3 (JAK3) in bovine preovulatory follicles and identification of JAK3 interacting proteins in granulosa cells." in: Journal of ovarian research, Vol. 9, Issue 1, pp. 71, (2016) (PubMed).

  • 抗原

    INHBA (Inhibin, beta A (INHBA))

    别名

    INHBA

    背景

    The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
    Alias Symbols: EDF, FRP
    Protein Interaction Partner: ACVRL1, ACVR2B, ACVR2A, ACVR1, FST, IGSF1, CHRDL2, FSTL3, IGFBP7, ACVR1B, INHBC, TGFBR3, INHBB, INHA, INHBA, ENG,
    Protein Size: 426

    分子量

    44 kDa

    基因ID

    3624

    NCBI登录号

    NM_002192, NP_002183

    UniProt

    P08476

    途径

    Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Autophagy
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