ARAF 抗体 (Middle Region)
Quick Overview for ARAF 抗体 (Middle Region) (ABIN2785788)
抗原
See all ARAF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- PRGSPSPASV SSGRKSPHSK SPAEQRERKS LADDKKKVKN LGYRDSGYYW
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预测反应
- Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%
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产品特性
- This is a rabbit polyclonal antibody against ARAF. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ARAF
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 606 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ARAF (V-Raf Murine Sarcoma 3611 Viral Oncogene Homolog (ARAF))
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别名
- ARAF
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背景
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ARAF belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily. It contains 1 phorbol-ester/DAG-type zinc finger, 1 protein kinase domain, and 1 RBD (Ras-binding) domain. ARAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus.
Alias Symbols: A-RAF, ARAF1, PKS2, RAFA1
Protein Interaction Partner: AGTRAP, KRAS, CDC37, MAP2K1, GNA12, FKBP5, UBC, RNF2, FBXO6, YWHAB, HIPK4, YWHAE, RRAS2, BAD, TEKT4P2, WNK1, NELFCD, DIDO1, TESK1, MAP2K2, MLH1, HSP90AA1, E2F6, BRAF, TIRAP, IRF7, IRAK2, YWHAG, MYO18A, CHD6, YWHAZ, PBK, NUDT14, KLHL12, COPS3, TIMM44, ASS1
Protein Size: 606 -
分子量
- 67 kDa
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基因ID
- 369
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NCBI登录号
- NM_001654, NP_001645
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UniProt
- P10398
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途径
- MAPK Pathway, RTK signaling, Hepatitis C
抗原
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