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JAK3 抗体 (Middle Region)

This anti-JAK3 antibody is a 兔多克隆 antibody detecting JAK3 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 马和 Pig.

WB Suggested Anti-JAK3 Antibody Titration: 0. (JAK3 抗体 (Middle Region))

1 image

产品编号 ABIN2785645

发货至: 中国

Quick Overview for JAK3 抗体 (Middle Region) (ABIN2785645)

抗原

See all JAK3 抗体

JAK3 (Janus Kinase 3 (JAK3))

适用

80
44
20
1
1
1
1
1
1
1

人, 小鼠, 大鼠, Cow, 犬, 马, Pig

宿主

兔

克隆类型

多克隆

标记

43
7
4
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1

This JAK3 antibody is un-conjugated

应用范围

54
31
18
17
14
14
12
12
8
8
3
1
1

Western Blotting (WB)

Discover our top product JAK3 Primary Antibody

抗原表位
16

8

7

5

4

4

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Middle Region

序列

KLLPLDKDYY VVREPGQSPI FWYAPESLSD NIFSRQSDVW SFGVVLYELF

预测反应

Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against JAK3. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human JAK3
anti-Janus Kinase 3 (JAK3) (AA 716-967) antibody
JAK3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 3 (JAK3) antibody
JAK3 适用: 人, 小鼠 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5H2 unconjugated

anti-Janus Kinase 3 (JAK3) (AA 601-700) antibody
JAK3 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 3 (JAK3) antibody
JAK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 3 (JAK3) (pTyr980), (pTyr981) antibody
JAK3 适用: 人 ELISA 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 3 (JAK3) (Tyr785) antibody
JAK3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 3 (JAK3) (AA 750-850) antibody
JAK3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 3 (JAK3) (AA 751-800) antibody
JAK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 3 (JAK3) antibody
JAK3 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 1C7 unconjugated Recombinant Antibody

anti-Janus Kinase 3 (JAK3) (pTyr785) antibody
JAK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 1124 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

JAK3 (Janus Kinase 3 (JAK3))

别名

JAK3

背景

JAK3 is a member of the Janus kinase (JAK) family of tyrosine kinases, which is involved in cytokine receptor-mediated intracellular signal transduction. JAK3 is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in JAK3 are associated with autosomal SCID (severe combined immunodeficiency disease).The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
Protein Interaction Partner: Socs5, KIT, IL7R, TYK2, STAT6, STAT3, JAK2, JAK1, IL4R, GTF2B, ERBB3, CDK1, CD81, APOA1, UBC, SOCS3, UHRF2, STAT5A, IKBKG, ALK, SH2B2, TIAF1, INPP5D, PTPN2, STAM2, PRMT5, SOCS1, KHDRBS1, STAM, PTK2B, IRS2, SHB, JAK3, IL2RG, VIL1, FES, CD247, PTPN6, PIK3R1
Protein Size: 1124

分子量

125 kDa

基因ID

3718

NCBI登录号

NM_000215, NP_000206

UniProt

P52333

途径

JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response

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