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JAK3 抗体 (N-Term)

The 兔 多克隆 anti-JAK3 antibody (ABIN2785644) specifically detects JAK3 in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 马, Pig 和 豚鼠 samples.
产品编号 ABIN2785644
发货至: 中国
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Quick Overview for JAK3 抗体 (N-Term) (ABIN2785644)

抗原

See all JAK3 抗体
JAK3 (Janus Kinase 3 (JAK3))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 豚鼠

宿主

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克隆类型

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多克隆

标记

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This JAK3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    APPSEETPLI PQRSCSLLST EAGALHVLLP ARGPGPPQRL SFSFGDHLAE

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against JAK3. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N-terminal region of human JAK3
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    JAK3 (Janus Kinase 3 (JAK3))

    别名

    JAK3

    背景

    The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
    Alias Symbols: JAKL, LJAK, JAK-3, L-JAK, JAK3_HUMAN
    Protein Size: 619

    分子量

    68 kDa

    基因ID

    3718

    NCBI登录号

    NM_000215, NP_000206

    UniProt

    Q8N1E8

    途径

    JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
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