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Gelsolin 抗体 (C-Term)

GSN 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 马, 绵羊, 斑马鱼, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785642
发货至: 中国
  • 抗原 See all Gelsolin (GSN) 抗体
    Gelsolin (GSN)
    抗原表位
    • 16
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 89
    • 30
    • 23
    • 9
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 兔, 犬, 马, 绵羊, 斑马鱼, 豚鼠
    宿主
    • 74
    • 24
    • 2
    克隆类型
    • 68
    • 32
    多克隆
    标记
    • 56
    • 9
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Gelsolin antibody is un-conjugated
    应用范围
    • 77
    • 29
    • 22
    • 20
    • 19
    • 17
    • 15
    • 14
    • 13
    • 9
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    KPMIIYKGGT SREGGQTAPA STRLFQVRAN SAGATRAVEV LPKAGALNSN
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against GSN. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human GSN
    Top Product
    Discover our top product GSN Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 782 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Shokouhi, Khosroshahi: "Ardalan-Shoja-Kiuru syndrome--hereditary gelsolin amyloidosis plus retinitis pigmentosa." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 23, Issue 3, pp. 1071; author reply 1071-2, (2008) (PubMed).

  • 抗原
    Gelsolin (GSN)
    别名
    GSN (GSN 产品)
    别名
    ADF antibody, AGEL antibody, CG1106 antibody, DGS antibody, Dmel\\CG1106 antibody, gel antibody, scin antibody, cb107 antibody, gsn antibody, sb:cb107 antibody, u-gelsolin antibody, wu:fi16f06 antibody, gelsolin antibody, Gelsolin antibody, gelsolin S homeolog antibody, gelsolin a antibody, GSN antibody, Gel antibody, Gsn antibody, gsn.S antibody, gsn antibody, gsna antibody
    背景
    GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. It is a calcium-regulated protein, which functions in both assembly and disassembly of actin filaments. Defects in the gene encoding GSN are a cause of familial amyloidosis Finnish type (FAF).The protein encoded by this gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
    Alias Symbols: DKFZp313L0718, ADF, AGEL
    Protein Interaction Partner: ITCH, CFLAR, TP53, UBC, CASP3, UBD, FN1, MPG, ESR1, ALB, SDHB, ACTA1, MDM2, UBE2Q2, FBXO25, ARRB2, ARRB1, AR, PSMD4, TNIK, CLIC5, TOM1L1, ACTN4, VDAC1, BCAR1, PXN, LIMK2, VASP, PIK3CG, PTK2B, FHIT, VCL, CSK, APP, ACTB, ACTG1, PLCG1, SRC, PTPN12, PTK2, PIK
    Protein Size: 782
    分子量
    83 kDa
    基因ID
    2934
    NCBI登录号
    NM_000177, NP_000168
    UniProt
    P06396
    途径
    Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy
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