Gelsolin 抗体 (C-Term)
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北京 101111
Quick Overview for Gelsolin 抗体 (C-Term) (ABIN2785642)
抗原
See all Gelsolin (GSN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- GSN Antibody - C-terminal region
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序列
- KPMIIYKGGT SREGGQTAPA STRLFQVRAN SAGATRAVEV LPKAGALNSN
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against GSN. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human GSN
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anti-Gelsolin (GSN) (AA 170-423) antibody
GSN 适用: Cow WB, IHC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Gelsolin (GSN) antibodyGSN 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5E3B9 unconjugated
anti-Gelsolin (GSN) (AA 543-782) antibodyGSN 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Gelsolin (GSN) (AA 674-782) antibodyGSN 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Gelsolin (GSN) (AA 577-771) antibodyGSN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gelsolin (GSN) (AA 673-782) antibodyGSN 适用: 人 WB, IP, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3G5 unconjugated
anti-Gelsolin (GSN) (AA 432-553) antibodyGSN 适用: 人 WB 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Gelsolin (GSN) (AA 432-625) antibodyGSN 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gelsolin (GSN) (C-Term) antibodyKO Validated GSN 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Gelsolin (GSN) (AA 1-782) antibodyGSN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54299-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Ardalan-Shoja-Kiuru syndrome--hereditary gelsolin amyloidosis plus retinitis pigmentosa." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 23, Issue 3, pp. 1071; author reply 1071-2, (2008) (PubMed).
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- Gelsolin (GSN)
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别名
- GSN
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背景
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Background Information: GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. It is a calcium-regulated protein, which functions in both assembly and disassembly of actin filaments. Defects in the gene encoding GSN are a cause of familial amyloidosis Finnish type (FAF).The protein encoded by this gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
Gene Name: Gelsolin
Alternative Symbols: ADF, AGEL
Protein Name: Gelsolin
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分子量
- 83kDa
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基因ID
- 2934
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NCBI登录号
- NP_000168
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UniProt
- P06396
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途径
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy
抗原
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