SOCS7 抗体 (N-Term)
Quick Overview for SOCS7 抗体 (N-Term) (ABIN2785525)
抗原
See all SOCS7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GSAGRELDAG RKPKLTRTQS AFSPVSFSPL FTGETVSLVD VDISQRGLTS
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预测反应
- Cow: 100%, Dog: 92%, Guinea Pig: 83%, Horse: 100%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 100%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against SOCS7. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human SOCS7
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anti-Suppressor of Cytokine Signaling 7 (SOCS7) (AA 6-165) antibody
SOCS7 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 7 (SOCS7) (Internal Region) antibodyVerified SOCS7 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 7 (SOCS7) (AA 35-84) antibodySOCS7 适用: 人, 小鼠, 大鼠, Cow, 兔, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 7 (SOCS7) (N-Term) antibodySOCS7 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 7 (SOCS7) (AA 458-486) antibodySOCS7 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))
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别名
- SOCS7
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背景
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SOCS7 regulates signaling cascades probably through protein ubiquitination and/or sequestration. It functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. It inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. SOCS7 may be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Protein Interaction Partner: SEPT6, SORBS3, STAT5A, STAT3, CUL5, IRS4, PIK3R2, TUBB4B, TUBA1A, IRS2, NCK1, PLCG1, PIK3R1, EGFR, GRB2,
Protein Size: 331 -
分子量
- 36 kDa
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基因ID
- 30837
抗原
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