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Endonuclease G 抗体 (Middle Region)

There is 1 publication for this product available. The 兔 多克隆 anti-Endonuclease G antibody is suitable to detect Endonuclease G in samples from 人, 大鼠, 小鼠, 犬, 豚鼠, 马, 斑马鱼 和 Cow. It has been validated for WB.
产品编号 ABIN2784751
发货至: 中国
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Quick Overview for Endonuclease G 抗体 (Middle Region) (ABIN2784751)

抗原

See all Endonuclease G (ENDOG) 抗体
Endonuclease G (ENDOG)

适用

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人, 大鼠, 小鼠, 犬, 豚鼠, 马, 斑马鱼, Cow

宿主

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克隆类型

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多克隆

标记

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This Endonuclease G antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    YVMPNAPVDE AIPLERFLVP IESIERASGL LFVPNILARA GSLKAITAGS

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against ENDOG. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human ENDOG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 297 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Guha, Bandyopadhyaya, Polumuri, Chumsri, Gade, Kalvakolanu, Ahmed et al.: "Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic ..." in: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 5-22, (2014) (PubMed).

  • 抗原

    Endonuclease G (ENDOG)

    别名

    ENDOG

    背景

    ENDOG cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, ENDOG also has ribonuclease (RNase) and RNase H activities. ENDOG is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.
    Alias Symbols: FLJ27463
    Protein Interaction Partner: UBC, BIRC2, DNAJA4, STUB1, HSPA4, AIFM1, FEN1,
    Protein Size: 297

    分子量

    28 kDa

    基因ID

    2021

    NCBI登录号

    NM_004435, NP_004426

    UniProt

    Q14249

    途径

    Apoptosis
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