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- 抗原 See all OAS1 抗体
- OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This OAS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- GWRQLAQEAE AWLNYPCFKN WDGSPVSSWI LLVRPPASSL PFIPAPLHEA
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against OAS1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human OAS1
- Top Product
- Discover our top product OAS1 Primary Antibody
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anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 74-165) antibody
OAS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 139-358) antibodyOAS1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (C-Term) antibodyOAS1 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 302-330), (C-Term) antibodyOAS1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1937 unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (Middle Region) antibodyOAS1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 74-165) antibodyOAS1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 296-395) antibodyOAS1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-364) antibodyOAS1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-400) antibodyOAS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (C-Term) antibodyOAS1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 364 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
- 别名
- OAS1 (OAS1 产品)
- 别名
- OAS1 antibody, IFI-4 antibody, OIAS antibody, OIASI antibody, L3 antibody, Pp2a2 antibody, 2',5'-oligoadenylate synthetase 1 antibody, 2'-5'-oligoadenylate synthetase 1 antibody, 2'-5' oligoadenylate synthetase 1A antibody, protein phosphatase 2 catalytic subunit beta antibody, OAS1 antibody, Oas1a antibody, Ppp2cb antibody, Oas1 antibody
- 背景
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OAS1 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Mutations in this gene have been associated with host susceptibility to viral infection.This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: IFI-4, OIAS, OIASI
Protein Interaction Partner: EXOC5, TRIM27, ACTN1, PRMT6, WBSCR22, RPL30, HCVgp1,
Protein Size: 364 - 分子量
- 42 kDa
- 基因ID
- 4938
- NCBI登录号
- NM_002534, NP_002525
- 途径
- Hepatitis C
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