Tec Protein Tyrosine Kinase (TEC) (Middle Region) 抗体
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Quick Overview for Tec Protein Tyrosine Kinase (TEC) (Middle Region) 抗体 (ABIN2784460)
抗原
See all Tec Protein Tyrosine Kinase (TEC) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- VKVSDFGMAR YVLDDQYTSS SGAKFPVKWC PPEVFNYSRF SSKSDVWSFG
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
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产品特性
- This is a rabbit polyclonal antibody against TEC. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TEC
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 631 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Tec Protein Tyrosine Kinase (TEC)
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别名
- TEC
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背景
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The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
Alias Symbols: MGC126760, MGC126762, PSCTK4
Protein Interaction Partner: ERBB2, MED28, GRB2, SHC1, FASLG, Nedd4, UBC, IKBKG, STAP1, PIP4K2A, PLK4, PTPN18, PIK3R3, GNA12, SOCS1, PIP5K1A, PTPN21, DOK1, TEC, PLCG2, WAS, BTK, BMX, TP53, PRLR, PLCG1, PIK3R1, LYN, KIT, VAV1, JAK2, JAK1, ARHGEF12, GNA13, RHOA, RAC1, PIK3R2,
Protein Size: 631 -
分子量
- 73 kDa
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基因ID
- 7006
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NCBI登录号
- NM_003215, NP_003206
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UniProt
- P42680
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途径
- Fc-epsilon Receptor Signaling Pathway
抗原
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