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Tec Protein Tyrosine Kinase (TEC) (Middle Region) 抗体

This 兔 多克隆 antibody specifically detects Tec Protein Tyrosine Kinase in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 和 斑马鱼.
产品编号 ABIN2784460
发货至: 中国
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Quick Overview for Tec Protein Tyrosine Kinase (TEC) (Middle Region) 抗体 (ABIN2784460)

抗原

See all Tec Protein Tyrosine Kinase (TEC) 抗体
Tec Protein Tyrosine Kinase (TEC)

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼

宿主

  • 66
  • 4

克隆类型

  • 55
  • 15
多克隆

标记

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非结合性

应用范围

  • 67
  • 28
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  • 7
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Western Blotting (WB)
  • 抗原表位

    • 15
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    Middle Region

    序列

    VKVSDFGMAR YVLDDQYTSS SGAKFPVKWC PPEVFNYSRF SSKSDVWSFG

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

    产品特性

    This is a rabbit polyclonal antibody against TEC. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human TEC
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 631 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Tec Protein Tyrosine Kinase (TEC)

    别名

    TEC

    背景

    The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
    Alias Symbols: MGC126760, MGC126762, PSCTK4
    Protein Interaction Partner: ERBB2, MED28, GRB2, SHC1, FASLG, Nedd4, UBC, IKBKG, STAP1, PIP4K2A, PLK4, PTPN18, PIK3R3, GNA12, SOCS1, PIP5K1A, PTPN21, DOK1, TEC, PLCG2, WAS, BTK, BMX, TP53, PRLR, PLCG1, PIK3R1, LYN, KIT, VAV1, JAK2, JAK1, ARHGEF12, GNA13, RHOA, RAC1, PIK3R2,
    Protein Size: 631

    分子量

    73 kDa

    基因ID

    7006

    NCBI登录号

    NM_003215, NP_003206

    UniProt

    P42680

    途径

    Fc-epsilon Receptor Signaling Pathway
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