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YBX1 抗体 (C-Term)

This anti-YBX1 antibody is a 兔 多克隆 antibody detecting YBX1 in WB 和 IHC. Suitable for 人, 大鼠, 小鼠, Cow, 犬, Pig, 绵羊, 马, 兔 和 豚鼠.
产品编号 ABIN2784387
发货至: 中国

Quick Overview for YBX1 抗体 (C-Term) (ABIN2784387)

抗原

See all YBX1 抗体
YBX1 (Y Box Binding Protein 1 (YBX1))

适用

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人, 大鼠, 小鼠, Cow, 犬, Pig, 绵羊, 马, 兔, 豚鼠

宿主

  • 91
  • 32

克隆类型

  • 82
  • 41
多克隆

标记

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This YBX1 antibody is un-conjugated

应用范围

  • 82
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 25
    • 7
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    C-Term

    序列

    PYGRRPQYSN PPVQGEVMEG ADNQGAGEQG RPVRQNMYRG YRPRFRRGPP

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 93%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

    产品特性

    This is a rabbit polyclonal antibody against YBX1. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human YBX1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    YBX1 (Y Box Binding Protein 1 (YBX1))

    别名

    YBX1

    背景

    YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. YBX1 binds and stabilizes cytoplasmic mRNA. YBX1 contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. YBX1 binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. YBX1 regulates the transcription of numerous genes. YBX1 promotes separation of DNA strands that contain mismatches or are modified by cisplatin. YBX1 has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). YBX1 may play a role in DNA repair. YBX1 is the component of the CRD-mediated complex that promotes MYC mRNA stability.
    Alias Symbols: BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1
    Protein Interaction Partner: UBC, TP53, AKT1, SPRTN, AURKA, SUMO2, STAU1, IVNS1ABP, SMURF2, EZH2, BMI1, SUZ12, RNF2, HNRNPU, HNRNPAB, HNRNPA2B1, FUS, FKBP3, DYNC1LI2, DYNC1I2, DYNC1H1, DDX1, APBB1, G3BP1, EIF2B2, TUBB, PRPF40A, EIF3K, DIMT1, TUBA4A, RPL23A, PTBP1, PA2G4, NMT1, MAP2,
    Protein Size: 324

    分子量

    35 kDa

    基因ID

    4904

    NCBI登录号

    NM_004559, NP_004550

    UniProt

    P67809

    途径

    Regulation of Muscle Cell Differentiation
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