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FIP200 抗体 (C-Term)

The 兔 多克隆 anti-FIP200 antibody (ABIN2784196) specifically detects FIP200 in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 和 斑马鱼 samples.
产品编号 ABIN2784196
发货至: 中国
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Quick Overview for FIP200 抗体 (C-Term) (ABIN2784196)

抗原

See all FIP200 (RB1CC1) 抗体
FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼

宿主

  • 44
  • 2

克隆类型

  • 44
  • 2
多克隆

标记

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This FIP200 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    序列

    SGASRRPWVL GKVMEKEYCQ AKKAQNRFKV PLGTKFYRVK AVSWNKKV

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against RB1CC1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human RB1CC1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1591 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))

    别名

    RB1CC1

    背景

    RB1CC1 is implicated in the regulation of RB1 expression. It functions as a DNA-binding transcription factor. RB1CC1 is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. The expression of RB1CC1 is, thus, a prerequisite for myogenic differentiation. RB1CC1 is frequently mutated in breast cancer and shows characteristics of a classical tumor suppressor gene.
    Alias Symbols: CC1, DRAGOU14, FIP200
    Protein Interaction Partner: ATG16L1, SESN2, ATG5, UBC, EXOC1, DYRK2, PINK1, CALCOCO2, RFWD2, CTNNB1, GABARAPL1, GABARAP, VHL, RNF111, SMARCB1, SKIL, SKI, TBKBP1, TP53, ATG13, ULK2, SAFB2, ULK1, SAFB, RPA2, RPA1, PRKAB2, PRKAA2, HSBP1, MAP1LC3C, SMCR8, ATG101, YLPM1, TBK1, RBMX, PTK2
    Protein Size: 1591

    分子量

    183 kDa

    基因ID

    9821

    NCBI登录号

    NM_001083617, NP_001077086

    UniProt

    Q8TDY2

    途径

    Regulation of Cell Size, Autophagy
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