DISP1 抗体 (Middle Region)
Quick Overview for DISP1 抗体 (Middle Region) (ABIN2784069)
抗原
See all DISP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- FVLCDVWNYT KFDKPHAETS ETVSITLQHA ALSMFVTSFT TAAAFYANYV
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预测反应
- Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 100%, Rat: 86%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against DISP1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human DISP1
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anti-Dispatched Homolog 1 (DISP1) (C-Term) antibody
Verified DISP1 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Dispatched Homolog 1 (DISP1) (AA 1141-1435) antibodyDISP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dispatched Homolog 1 (DISP1) (AA 575-624) antibodyDISP1 适用: 人, 大鼠, 兔, 斑马鱼, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Dispatched Homolog 1 (DISP1) (AA 1325-1524) antibodyDISP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1524 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DISP1 (Dispatched Homolog 1 (DISP1))
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别名
- DISP1
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背景
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DISP1 functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal.The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo.
Alias Symbols: DISPA, DKFZP434I0428, FLJ43740, MGC104180, MGC13130, MGC16796
Protein Interaction Partner: LAPTM5, UBC,
Protein Size: 1524 -
分子量
- 171 kDa
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基因ID
- 84976
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NCBI登录号
- NM_032890, NP_116279
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UniProt
- Q96F81
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途径
- Hedgehog Signaling
抗原
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