MAP3K2 抗体 (N-Term)
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北京 101111
Quick Overview for MAP3K2 抗体 (N-Term) (ABIN2783679)
抗原
See all MAP3K2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- AERKKRLSII GPTSRDRSSP PPGYIPDELH QVARNGSFTS INSEGEFIPE
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 80%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against MAP3K2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MAP3K2
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anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) antibody
MAP3K2 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 4B4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) antibodyKD Validated MAP3K2 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB260 unconjugated Recombinant Antibody
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 357-619) antibodyMAP3K2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 111-200) antibodyMAP3K2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 14-43), (N-Term) antibodyMAP3K2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34479 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (C-Term) antibodyMAP3K2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 146-195) antibodyMAP3K2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 619 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))
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别名
- MAP3K2
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背景
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MAP3K2 is a component of a protein kinase signal transduction cascade. It regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7. It also plays a role in caveolae kiss-and-run dynamics.The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-18 AF111105.1 37-54 19-79 AI760702.1 474-534 80-371 AF111105.1 116-407 372-2650 AB208963.1 313-2591 2651-3557 AK075004.1 2050-2956 3558-3571 BQ423724.1 71-84 3572-3577 W07290.1 11-16 3578-4302 AK074577.1 1-725 4303-4421 BM470563.1 21-139 4422-4424 AK074577.1 845-847 4425-4941 BM470563.1 142-658
Alias Symbols: MEKK2, MEKK2B
Protein Interaction Partner: MAP3K2, STAMBP, USP2, UBC, MAP2K7, MAP2K5, MAPK7, MAP3K3, XIAP, BIRC2, YWHAB, YWHAE, HSP90AA1, STK38, MAP2K4, MAP2K3, SMURF1, NEDD4, NEDD4L, Stub1, YWHAG, PIBF1, IKBKG, WNK1, SH2D2A, PKN2, MAP3K5, YWHAZ, MAPK8, NFKBIA, SFN,
Protein Size: 619 -
分子量
- 70 kDa
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基因ID
- 10746
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NCBI登录号
- NM_006609, NP_006600
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UniProt
- Q9Y2U5
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途径
- MAPK Pathway
抗原
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