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MEK2 抗体 (C-Term)

Name: MEK2 抗体 (C-Term)
SKU: ABIN2783573
Availability: OutOfStock

This anti-MEK2 antibody is a 兔多克隆 antibody detecting MEK2 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, 豚鼠, Pig, Cow 和马.

WB Suggested Anti-MAP2K2 Antibody Titration: 0. (MEK2 抗体 (C-Term))

IHC

MAP2K2 antibody - C-terminal region Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue Observed Staining: Cytoplasm of pneumocytes Primary Antibody Concentration: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (MEK2 抗体 (C-Term))

IHC

3 images

产品编号 ABIN2783573

发货至: 中国

Datasheet as PDF

Quick Overview for MEK2 抗体 (C-Term) (ABIN2783573)

抗原

See all MEK2 (MAP2K2) 抗体

MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

适用

人, 小鼠, 大鼠, 犬, 豚鼠, Pig, Cow, 马

宿主

兔

克隆类型

多克隆

标记

This MEK2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product MAP2K2 Primary Antibody

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C-Term

序列

IKNPAERADL KMLTNHTFIK RSEVEEVDFA GWLCKTLRLN QPGTPTRTAV

预测反应

Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 93%, Rat: 92%

产品特性

This is a rabbit polyclonal antibody against MAP2K2. It was validated on Western Blot and immunohistochemistry.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human MAP2K2
anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-50) antibody
MAP2K2 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 44-313) antibody
MAP2K2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-30), (N-Term) antibody
MAP2K2 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal RB3595 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-400) antibody
MAP2K2 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-360) antibody
MAP2K2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 8D10 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-100) antibody
KO Validated MAP2K2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 200-229) antibody
MAP2K2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB12322 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 262-292) antibody
MAP2K2 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB3597 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 264-400) antibody
MAP2K2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (C-Term) antibody
MAP2K2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 400 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

别名

MAP2K2

背景

MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in MAP2K2 gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MAPKK2, MEK2, MKK2, PRKMK2
Protein Interaction Partner: CCNDBP1, RAF1, SUMO2, UBC, EGFR, IQGAP1, NFE2L2, YWHAB, MAPK1, PEX14, BRAF, ARAF, FAM65B, ZNF207, LIG4, MAPK8, WDR83, Ksr1, COPS5, MAP2K1, MEPCE, GRIN1, CNKSR1, LAMTOR3, GRIN2D, RGS12, CASP9, MAPK3, MAP2K2, DUSP3, Flna,
Protein Size: 400

分子量

44 kDa

基因ID

5605

NCBI登录号

NM_030662, NP_109587

UniProt

P36507

途径

MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling