Manic Fringe 抗体 (C-Term)
Quick Overview for Manic Fringe 抗体 (C-Term) (ABIN2783426)
抗原
See all Manic Fringe (MFNG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- QLLRTAQLPE QVTLSYGVFE GKLNVIKLQG PFSPEEDPSR FRSLHCLLYP
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预测反应
- Cow: 92%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%
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产品特性
- This is a rabbit polyclonal antibody against MFNG. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human MFNG
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anti-MFNG (MFNG) (AA 214-291) antibody
MFNG 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-MFNG (MFNG) (C-Term) antibodyMFNG 适用: 人, 犬, 马, 豚鼠, 兔, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MFNG (MFNG) (Internal Region) antibodyMFNG 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-MFNG (MFNG) (AA 56-309) antibodyMFNG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-MFNG (MFNG) (AA 221-321) antibodyMFNG 适用: 小鼠 ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-MFNG (MFNG) antibodyMFNG 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-MFNG (MFNG) (AA 28-321) antibodyMFNG 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MFNG (MFNG) (AA 214-291) antibodyMFNG 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-MFNG (MFNG) (AA 1-321) antibodyMFNG 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-MFNG (MFNG) (AA 211-260) antibodyMFNG 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 兔, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 321 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Manic Fringe (MFNG) (MFNG)
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别名
- MFNG
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背景
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MFNG is one of the evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene is a member of the fringe gene family which also includes Radical and Lunatic fringe. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta1,3 N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: DLL1, JAG1, NOTCH2, NOTCH1,
Protein Size: 321 -
分子量
- 36 kDa
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基因ID
- 4242
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NCBI登录号
- NM_002405, NP_002396
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UniProt
- O00587
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途径
- Notch Signaling
抗原
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