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MAPT 抗体 (Middle Region)

MAPT 适用: 人, 小鼠, 大鼠, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2783223
发货至: 中国
  • 抗原 See all MAPT 抗体
    MAPT (Microtubule-Associated Protein tau (MAPT))
    抗原表位
    • 11
    • 9
    • 9
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    • 6
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    • 1
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    • 1
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    • 1
    • 1
    • 1
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    Middle Region
    适用
    • 213
    • 109
    • 99
    • 15
    • 12
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    • 5
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    • 3
    • 2
    • 2
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    人, 小鼠, 大鼠, Pig
    宿主
    • 200
    • 18
    • 6
    克隆类型
    • 194
    • 30
    多克隆
    标记
    • 178
    • 17
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 1
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    This MAPT antibody is un-conjugated
    应用范围
    • 194
    • 119
    • 60
    • 36
    • 25
    • 21
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    RGAAPPGQKG QANATRIPAK TPPAPKTPPS SGEPPKSGDR SGYSSPGSPG
    预测反应
    Human: 100%, Mouse: 86%, Pig: 79%, Rat: 86%
    产品特性
    This is a rabbit polyclonal antibody against MAPT. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human MAPT
    Top Product
    Discover our top product MAPT Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 441 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MAPT (Microtubule-Associated Protein tau (MAPT))
    别名
    MAPT (MAPT 产品)
    别名
    DDPAC antibody, FTDP-17 antibody, MAPTL antibody, MSTD antibody, MTBT1 antibody, MTBT2 antibody, PPND antibody, TAU antibody, AI413597 antibody, AW045860 antibody, Mtapt antibody, Tau antibody, RNPTAU antibody, pTau antibody, tau antibody, xtp antibody, MAPT antibody, PHF-tau antibody, slc6a6 antibody, taut antibody, wu:fc26e12 antibody, microtubule associated protein tau antibody, microtubule-associated protein tau antibody, microtubule associated protein tau S homeolog antibody, Microtubule-associated protein tau antibody, solute carrier family 6 (neurotransmitter transporter), member 6b antibody, MAPT antibody, Mapt antibody, mapt.S antibody, LOC5580230 antibody, CpipJ_CPIJ013260 antibody, tau antibody, slc6a6b antibody
    背景
    MAPT is differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. The mutations in the gene have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
    Alias Symbols: DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, TAU
    Protein Interaction Partner: Ywhaz, Prkaca, STUB1, PHGK, SRC, PRKAR1A, GSK3B, FYN, DCTN1, CSNK1A1, CDK2, AKT1, ABL1, YWHAQ, SGK1, MARK2, MARCH7, TUBB3, TUBA1B, UBC, TUBA4A, MARK4, PEG10, MARK3, MARK1, MAPK13, MAPK11, MAPK8, mapk14, Mapk12, LIMS1, HSPA1A, PPP5C, PPP2R4, CAPN2, PKN1, H
    Protein Size: 441
    分子量
    46 kDa
    基因ID
    4137
    NCBI登录号
    NM_005910, NP_005901
    途径
    MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size
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