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MAPT 抗体 (Middle Region)

The 兔 多克隆 anti-MAPT antibody (ABIN2783223) specifically detects MAPT in WB 和 IHC. The antibody is reactive with 人, 大鼠, 小鼠 和 Pig samples.
产品编号 ABIN2783223
发货至: 中国
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Quick Overview for MAPT 抗体 (Middle Region) (ABIN2783223)

抗原

See all MAPT 抗体
MAPT (Microtubule-Associated Protein tau (MAPT))

适用

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人, 大鼠, 小鼠, Pig

宿主

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克隆类型

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多克隆

标记

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This MAPT antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
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    Middle Region

    序列

    RGAAPPGQKG QANATRIPAK TPPAPKTPPS SGEPPKSGDR SGYSSPGSPG

    预测反应

    Human: 100%, Mouse: 86%, Pig: 79%, Rat: 86%

    产品特性

    This is a rabbit polyclonal antibody against MAPT. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human MAPT
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 441 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MAPT (Microtubule-Associated Protein tau (MAPT))

    别名

    MAPT

    背景

    MAPT is differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. The mutations in the gene have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
    Alias Symbols: DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, TAU
    Protein Interaction Partner: Ywhaz, Prkaca, STUB1, PHGK, SRC, PRKAR1A, GSK3B, FYN, DCTN1, CSNK1A1, CDK2, AKT1, ABL1, YWHAQ, SGK1, MARK2, MARCH7, TUBB3, TUBA1B, UBC, TUBA4A, MARK4, PEG10, MARK3, MARK1, MAPK13, MAPK11, MAPK8, mapk14, Mapk12, LIMS1, HSPA1A, PPP5C, PPP2R4, CAPN2, PKN1, H
    Protein Size: 441

    分子量

    46 kDa

    基因ID

    4137

    NCBI登录号

    NM_005910, NP_005901

    途径

    MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size
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