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MAPT 抗体 (Middle Region)

Name: MAPT 抗体 (Middle Region)
SKU: ABIN2783223
Availability: OutOfStock

This anti-MAPT antibody is a 兔多克隆 antibody detecting MAPT in WB 和 IHC. Suitable for 人, 大鼠, 小鼠和 Pig.

WB Suggested Anti-MAPT Antibody Titration: 0. (MAPT 抗体 (Middle Region))

WB Suggested Anti-MAPT Antibody Positive Control: Lane 1: 10ug N2A expressed human Tau-C Lane 2: 10ug N2A expressed human Tau-E Lane 3: 10ug N2A expressed human Tau-F Lane 4: 10ug N2A expressed human Tau-B Lane 5: 10ug N2A expressed human Fetal-Tau Lane 6: 10ug N2A expressed human Tau-D Lane 7: 10ug N2A expressed human much Fetal-Tau Lane 8: 10ug N2A lysate Primary Antibody Dilution : 1:2000 Secondary Antibody : Donkey anti-rabbit-HRP Secondry Antibody Dilution : 1:10,000 Submitted by: Max Holzer, Paul Flechsig Institut of Brain Research, University of Leipzig (MAPT 抗体 (Middle Region))

Researcher: Max Holzer, Paul Flechsig Institut of Brain Research, University of Leipzig Application: Western blotting Species + Tissue/Cell type: Lane 1: 10ug E. (MAPT 抗体 (Middle Region))

Sample Type : A: Transgenic hTau P301L mouse cortex B: Tau-Ko mouse cortex C: WT mouse cortex Primary Antibody Dilution : 1:1000 Secondary Antibody : Anti-rabbit-biotin / Avidin-HRP Secondary Antibody Dilution : 1:1000 /1:2000 Color/Signal Descriptions : Dark grey: MAPT Gene Name : MAPT Submitted by : Max Holzer, Paul Flechsig Institut of Brain Research, University of Leipzig (MAPT 抗体 (Middle Region))

IHC

4 images

产品编号 ABIN2783223

发货至: 中国

Quick Overview for MAPT 抗体 (Middle Region) (ABIN2783223)

抗原

See all MAPT 抗体

MAPT (Microtubule-Associated Protein tau (MAPT))

适用

人, 大鼠, 小鼠, Pig

宿主

兔

克隆类型

多克隆

标记

This MAPT antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product MAPT Primary Antibody

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Middle Region

序列

RGAAPPGQKG QANATRIPAK TPPAPKTPPS SGEPPKSGDR SGYSSPGSPG

预测反应

Human: 100%, Mouse: 86%, Pig: 79%, Rat: 86%

产品特性

This is a rabbit polyclonal antibody against MAPT. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human MAPT
anti-Microtubule-Associated Protein tau (MAPT) (pThr212) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer262) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer235) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (AA 130-386) antibody
MAPT 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (AA 34-368) antibody
MAPT 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pThr181) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pThr205) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer404) antibody
MAPT 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer422) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer356) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 441 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

MAPT (Microtubule-Associated Protein tau (MAPT))

别名

MAPT

背景

MAPT is differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. The mutations in the gene have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Alias Symbols: DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, TAU
Protein Interaction Partner: Ywhaz, Prkaca, STUB1, PHGK, SRC, PRKAR1A, GSK3B, FYN, DCTN1, CSNK1A1, CDK2, AKT1, ABL1, YWHAQ, SGK1, MARK2, MARCH7, TUBB3, TUBA1B, UBC, TUBA4A, MARK4, PEG10, MARK3, MARK1, MAPK13, MAPK11, MAPK8, mapk14, Mapk12, LIMS1, HSPA1A, PPP5C, PPP2R4, CAPN2, PKN1, H
Protein Size: 441

分子量

46 kDa

基因ID

4137

NCBI登录号

NM_005910, NP_005901

途径

MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size