PRAS40 抗体 (C-Term)
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北京 101111
Quick Overview for PRAS40 抗体 (C-Term) (ABIN2783209)
抗原
See all PRAS40 (AKT1S1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- AKT1S1 Antibody - C-terminal region
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序列
- KSLPVSVPVW GFKEKRTEAR SSDEENGPPS SPDLDRIAAS MRALVLREAE
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against AKT1S1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human AKT1S1
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anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 92-276) antibody
AKT1S1 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 6H1C6 unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (pThr246) antibodyKD Validated AKT1S1 适用: 人 WB, IF (p), FACS 宿主: 兔 Monoclonal 23GB3855 unconjugated Recombinant Antibody
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 92-276) antibodyAKT1S1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4A11G7 unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 152-276) antibodyAKT1S1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) antibodyKD Validated AKT1S1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB645 unconjugated Recombinant Antibody
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 52-101) antibodyAKT1S1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) antibodyKD Validated AKT1S1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB640 unconjugated Recombinant Antibody
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (pThr246) antibodyAKT1S1 适用: 人 WB, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) antibodyAKT1S1 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 132-256) antibodyAKT1S1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48061-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))
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别名
- AKT1S1
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背景
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Background Information: AKT1S1 may play an important role in phosphatidylinositol 3-kinase (PI3K)-AKT1 survival signaling. It is the substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. Its role in survival signaling pathways may be modulated by oxidative stress. AKT1S1 may also play a role in nerve growth factor-mediated neuroprotection.AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM].
Gene Name: AKT1 substrate 1 (proline-rich)
Alternative Symbols: Lobe, PRAS40
Protein Name: Proline-rich AKT1 substrate 1
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分子量
- 27kDa
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基因ID
- 84335
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NCBI登录号
- NP_115751
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UniProt
- Q96B36
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Autophagy, BCR Signaling, Warburg Effect
抗原
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