PRAS40 抗体 (C-Term)
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- 抗原 See all PRAS40 (AKT1S1) 抗体
- PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRAS40 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- KSLPVSVPVW GFKEKRTEAR SSDEENGPPS SPDLDRIAAS MRALVLREAE
- 预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against AKT1S1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human AKT1S1
- Top Product
- Discover our top product AKT1S1 Primary Antibody
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anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 92-276) antibody
AKT1S1 适用: 人 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 6H1C6 unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 152-276) antibodyAKT1S1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 92-276) antibodyAKT1S1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4A11G7 unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 52-101) antibodyAKT1S1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (pThr246) antibodyAKT1S1 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 132-256) antibodyAKT1S1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (Ser363) antibodyAKT1S1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) antibodyAKT1S1 适用: 人 WB, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 227-256) antibodyAKT1S1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) antibodyAKT1S1 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 1997CT730-74-73 unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 256 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))
- 别名
- AKT1S1 (AKT1S1 产品)
- 别名
- MGC81452 antibody, lobe antibody, pras40 antibody, fb34a04 antibody, wu:fb34a04 antibody, Lobe antibody, PRAS40 antibody, 1110012J22Rik antibody, AI227026 antibody, Lobel antibody, AKT1 substrate 1 (proline rich) S homeolog antibody, AKT1 substrate 1 antibody, AKT1 substrate 1 (proline rich) antibody, AKT1 substrate 1 (proline-rich) antibody, akt1s1.S antibody, AKT1S1 antibody, akt1s1 antibody, Akt1s1 antibody
- 背景
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AKT1S1 may play an important role in phosphatidylinositol 3-kinase (PI3K)-AKT1 survival signaling. It is the substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. Its role in survival signaling pathways may be modulated by oxidative stress. AKT1S1 may also play a role in nerve growth factor-mediated neuroprotection.AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM].
Alias Symbols: Lobe, MGC2865, PRAS40
Protein Interaction Partner: MTOR, RPTOR, SGK1, RICTOR, MAPKAP1, MLST8, FAM114A1, YWHAQ, YWHAB, SQSTM1, RPS6KA5, TCEA2, YWHAG, EIF6, AKT2, AKT1,
Protein Size: 256 - 分子量
- 27 kDa
- 基因ID
- 84335
- NCBI登录号
- NM_032375, NP_115751
- UniProt
- Q96B36
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Autophagy, BCR Signaling, Warburg Effect
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