14-3-3 zeta 抗体 (Middle Region)
Quick Overview for 14-3-3 zeta 抗体 (Middle Region) (ABIN2783207)
抗原
See all 14-3-3 zeta (YWHAZ) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- FDEAIAELDT LSEESYKDST LIMQLLRDNL TLWTSDTQGD EAEAGEGGEN
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against YWHAZ. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human YWHAZ
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anti-14-3-3 zeta (YWHAZ) (AA 133-212) antibody
YWHAZ 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 小鼠 Monoclonal 19G7E9 unconjugated
anti-14-3-3 zeta (YWHAZ) (AA 133-212) antibodyYWHAZ 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 zeta (YWHAZ) (AA 51-150) antibodyYWHAZ 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-14-3-3 zeta (YWHAZ) (pSer58) antibodyYWHAZ 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 zeta (YWHAZ) (Center) antibodyYWHAZ 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 zeta (YWHAZ) (pSer58) antibodyYWHAZ 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 zeta (YWHAZ) (AA 200-245) antibodyYWHAZ 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 zeta (YWHAZ) (Tyr330) antibodyYWHAZ 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 zeta (YWHAZ) (pThr232) antibodyYWHAZ 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 zeta (YWHAZ) (C-Term) antibodyYWHAZ 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 245 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 14-3-3 zeta (YWHAZ)
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别名
- YWHAZ
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背景
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YWHAZ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and sheep orthologs. The protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for this gene.
Alias Symbols: KCIP-1, MGC111427, MGC126532, MGC138156, YWHAD, 14-3-3-zeta
Protein Interaction Partner: FUS, UBC, HUWE1, MAPT, DTL, MAPK8, SGK1, ABL1, TSC2, DDIT4, SIK3, SIK2, SUMO2, STAU1, IRS4, MDM2, WWOX, YWHAZ, SNRPF, SNRPE, SLC9A3R1, LDHB, SFN, PFAS, PAK2, ERP44, MAPRE1, FERMT2, YWHAQ, PRMT5, YWHAH, YWHAG, VCL, UBE2V1, TGM2, EIF5, ECHS1, CAPNS1, ZFYVE1
Protein Size: 245 -
分子量
- 28 kDa
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基因ID
- 7534
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NCBI登录号
- NM_003406, NP_003397
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UniProt
- P63104
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途径
- Apoptosis, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
抗原
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