SIGLEC7 抗体 (Middle Region)
(1 reference)-
- 抗原 See all SIGLEC7 抗体
- SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
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抗原表位
- Middle Region
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适用
- 人, Cow, 犬, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIGLEC7 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- WRSLTLYPSQ PSNPLVLELQ VHLGDEGEFT CRAQNSLGSQ HVSLNLSLQQ
- 预测反应
- Cow: 85%, Dog: 100%, Guinea Pig: 86%, Horse: 92%, Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against SIGLEC7. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SIGLEC7
- Top Product
- Discover our top product SIGLEC7 Primary Antibody
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anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 377-467) antibody
SIGLEC7 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 38-121) antibodySIGLEC7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (N-Term) antibodySIGLEC7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) antibody (PE)SIGLEC7 适用: 人 FACS 宿主: 小鼠 Monoclonal 6-434 PE
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) antibodySIGLEC7 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 18-353) antibodySIGLEC7 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 1-467) antibodySIGLEC7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H1 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) antibodySIGLEC7 适用: 人 FACS 宿主: 小鼠 Monoclonal 6-434 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 18-353) antibodySIGLEC7 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 1-30), (N-Term) antibodySIGLEC7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2711 unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 467 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Differences in the constitutive and SIV infection induced expression of Siglecs by hematopoietic cells from non-human primates." in: Cellular immunology, Vol. 250, Issue 1-2, pp. 91-104, (2008) (PubMed).
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: "Differences in the constitutive and SIV infection induced expression of Siglecs by hematopoietic cells from non-human primates." in: Cellular immunology, Vol. 250, Issue 1-2, pp. 91-104, (2008) (PubMed).
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- 抗原
- SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
- 别名
- SIGLEC7 (SIGLEC7 产品)
- 别名
- SIGLEC7 antibody, AIRM1 antibody, CD328 antibody, CDw328 antibody, D-siglec antibody, QA79 antibody, SIGLEC-7 antibody, SIGLEC19P antibody, SIGLECP2 antibody, p75 antibody, p75/AIRM1 antibody, sialic acid-binding Ig-like lectin 7 antibody, sialic acid binding Ig like lectin 7 antibody, LOC468976 antibody, SIGLEC7 antibody
- 背景
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SIGLEC7 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. In the immune response, it may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. SIGLEC7 mediates inhibition of natural killer cells cytotoxicity. It may also play a role in hemopoiesis. SIGLEC7 inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
Alias Symbols: AIRM1, CDw328, D-siglec, QA79, SIGLEC-7, p75, p75/AIRM1, CD328
Protein Interaction Partner: SOCS3, TRAF4, PTPN11, GRB2,
Protein Size: 467 - 分子量
- 51 kDa
- 基因ID
- 27036
- NCBI登录号
- NM_014385, NP_055200
- UniProt
- Q9Y286
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