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CDT2/RAMP 抗体 (N-Term)

DTL 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782560
发货至: 中国
  • 抗原 See all CDT2/RAMP (DTL) 抗体
    CDT2/RAMP (DTL) (Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL))
    抗原表位
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 36
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马
    宿主
    • 36
    克隆类型
    • 34
    • 2
    多克隆
    标记
    • 21
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDT2/RAMP antibody is un-conjugated
    应用范围
    • 22
    • 14
    • 9
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    VNQISGAHNT SDKQTPSKPK KKQNSKGLAP SVDFQQSVTV VLFQDENTLV
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against DTL. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human DTL
    Top Product
    Discover our top product DTL Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 730 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    CDT2/RAMP (DTL) (Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL))
    别名
    DTL (DTL 产品)
    别名
    CDT2 antibody, DCAF2 antibody, L2DTL antibody, RAMP antibody, 2810047L02Rik antibody, 5730564G15Rik antibody, Ramp antibody, RGD1310439 antibody, cdt2 antibody, cdt2-a antibody, dcaf2 antibody, l2dtl antibody, ramp antibody, cb151 antibody, chunp6871 antibody, wu:fb54b02 antibody, denticleless E3 ubiquitin protein ligase homolog antibody, denticleless E3 ubiquitin protein ligase antibody, denticleless E3 ubiquitin protein ligase homolog S homeolog antibody, denticleless E3 ubiquitin protein ligase homolog (Drosophila) antibody, DTL antibody, Dtl antibody, dtl.S antibody, dtl antibody
    背景
    DTL is required for CDT1 proteolysis in response to DNA damage through the CUL4-DDB1 E3 ubiquitin-protein ligase. It seems to be necessary to ensure proper cell cycle regulation of DNA replication. DTL may function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. It also may play a role in cell proliferation of NT2 embryonal carcinoma cells.
    Alias Symbols: CDT2, DCAF2, L2DTL, RAMP
    Protein Interaction Partner: FBXO11, YWHAQ, CUL4A, YWHAZ, YWHAH, YWHAG, YWHAE, YWHAB, UBE2D1, UBC, PCNA, SFN, DDB1, FBXO18, CDT1, CUL4B, TDG, LYN, SHPRH, RAD18, COPS5, HLTF, CHEK1, CFTR, CDKN1A, DDA1, COPS4, COPS6, TOB1, COPS3, TUBG1, ATR, AURKB, TP53, MDM2, MSH2, MSH6, KAT2A, Dtl, S
    Protein Size: 730
    分子量
    79 kDa
    基因ID
    51514
    NCBI登录号
    NM_016448, NP_057532
    UniProt
    Q9NZJ0
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