CDT2/RAMP 抗体 (N-Term)
Quick Overview for CDT2/RAMP 抗体 (N-Term) (ABIN2782560)
抗原
See all CDT2/RAMP (DTL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- VNQISGAHNT SDKQTPSKPK KKQNSKGLAP SVDFQQSVTV VLFQDENTLV
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against DTL. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DTL
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anti-Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL) (AA 393-550) antibody
DTL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL) (AA 1-730) antibodyDTL 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL) (AA 229-256), (Middle Region) antibodyDTL 适用: 人, 小鼠 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL) (AA 182-231) antibodyDTL 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL) (AA 541-730) antibodyDTL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL) (AA 229-256) antibodyDTL 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB24420 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 730 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CDT2/RAMP (DTL) (Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL))
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别名
- DTL
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背景
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DTL is required for CDT1 proteolysis in response to DNA damage through the CUL4-DDB1 E3 ubiquitin-protein ligase. It seems to be necessary to ensure proper cell cycle regulation of DNA replication. DTL may function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. It also may play a role in cell proliferation of NT2 embryonal carcinoma cells.
Alias Symbols: CDT2, DCAF2, L2DTL, RAMP
Protein Interaction Partner: FBXO11, YWHAQ, CUL4A, YWHAZ, YWHAH, YWHAG, YWHAE, YWHAB, UBE2D1, UBC, PCNA, SFN, DDB1, FBXO18, CDT1, CUL4B, TDG, LYN, SHPRH, RAD18, COPS5, HLTF, CHEK1, CFTR, CDKN1A, DDA1, COPS4, COPS6, TOB1, COPS3, TUBG1, ATR, AURKB, TP53, MDM2, MSH2, MSH6, KAT2A, Dtl, S
Protein Size: 730 -
分子量
- 79 kDa
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基因ID
- 51514
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NCBI登录号
- NM_016448, NP_057532
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UniProt
- Q9NZJ0
抗原
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