DYRK1A 抗体 (N-Term)
Quick Overview for DYRK1A 抗体 (N-Term) (ABIN2782363)
抗原
See all DYRK1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- INEVYYAKKK RRHQQGQGDD SSHKKERKVY NDGYDDDNYD YIVKNGEKWM
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against DYRK1A. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DYRK1A
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anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A) (AA 674-763) antibody
DYRK1A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7D10 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A) (N-Term) antibodyDYRK1A 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A) (N-Term) antibodyDYRK1A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A) (AA 16-300) antibodyDYRK1A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A) (N-Term) antibodyVerified DYRK1A 适用: 人 WB, ELISA, IP 宿主: 山羊 Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A) (N-Term) antibodyDYRK1A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A) (AA 22-71) antibodyDYRK1A 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马, 猴, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A) (AA 624-763) antibodyDYRK1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A) (N-Term) antibodyDYRK1A 适用: 人, 大鼠, 兔 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A) (AA 107-136) antibodyDYRK1A 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 763 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
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别名
- DYRK1A
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背景
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This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms.
Alias Symbols: DYRK, DYRK1, HP86, MNB, MNBH, MRD7
Protein Interaction Partner: SUMO1, UBC, CCDC8, FAM117A, FAM53C, SIPA1L1, DCAF7, TROAP, KIAA0232, DYNLL1, RBL2, RBL1, RB1, ABCD3, PRKAR1A, FNTB, FNTA, EP300, DYRK1A, CREBBP, CCNA2, RNF169, FAM117B, DYNLL2, GLCCI1, PPP1R3F, LZTS2, PRKACB, PRKACA, TRAF3, BARD1, SNCA, MAP3K5, APP, SMAD3
Protein Size: 763 -
分子量
- 85 kDa
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基因ID
- 1859
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NCBI登录号
- NM_001396, NP_001387
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UniProt
- Q13627
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途径
- Mitotic G1-G1/S Phases
抗原
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