KLKB1 抗体 (Middle Region)
(1 reference)Quick Overview for KLKB1 抗体 (Middle Region) (ABIN2782312)
抗原
See all KLKB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- VLTAAHCFDG LPLQDVWRIY SGILNLSDIT KDTPFSQIKE IIIHQNYKVS
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预测反应
- Dog: 86%, Horse: 86%, Human: 100%, Pig: 79%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against KLKB1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human KLKB1
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anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) antibody
KLKB1 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (Internal Region) antibodyKLKB1 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (Cleaved-Arg390) antibodyKLKB1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (AA 503-612) antibodyKLKB1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) antibodyKLKB1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) antibodyKLKB1 适用: 人 ELISA, IHC, IHC (p), IEP 宿主: 绵羊 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (AA 20-300) antibodyKLKB1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (AA 391-638) antibodyKLKB1 适用: 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) antibodyKLKB1 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 9F6 unconjugated Recombinant Antibody
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (AA 341-390), (Cleaved-Arg390) antibodyKLKB1 适用: 人 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 638 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Expression, crystallization, and three-dimensional structure of the catalytic domain of human plasma kallikrein." in: The Journal of biological chemistry, Vol. 280, Issue 49, pp. 41077-89, (2005) (PubMed).
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: "Expression, crystallization, and three-dimensional structure of the catalytic domain of human plasma kallikrein." in: The Journal of biological chemistry, Vol. 280, Issue 49, pp. 41077-89, (2005) (PubMed).
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- KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))
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别名
- KLKB1
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背景
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Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.
Alias Symbols: KLK3, PPK
Protein Interaction Partner: TFPI2, HGFAC, SERPINA5, F12, KNG1, IGFBP3, HGF, MST1,
Protein Size: 638 -
分子量
- 28 kDa
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基因ID
- 3818
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NCBI登录号
- NM_000892, NP_000883
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UniProt
- P03952
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途径
- Complement System, Brown Fat Cell Differentiation
抗原
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