LTB 抗体 (N-Term)
Quick Overview for LTB 抗体 (N-Term) (ABIN2782173)
抗原
See all LTB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- AVPITVLAVL ALVPQDQGGL VTETADPGAQ AQQGLGFQKL PEEEPETDLS
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预测反应
- Guinea Pig: 79%, Horse: 91%, Human: 100%, Rabbit: 100%
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产品特性
- This is a rabbit polyclonal antibody against LTB. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human LTB
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 244 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
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别名
- LTB
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背景
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Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: TNFC, TNFSF3, p33
Protein Interaction Partner: TNFSF14, LTBR, LTB, TNFRSF1A, LTA,
Protein Size: 244 -
分子量
- 25 kDa
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基因ID
- 4050
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NCBI登录号
- NM_002341, NP_002332
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UniProt
- Q06643
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途径
- NF-kappaB Signaling
抗原
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