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Indian Hedgehog 抗体 (N-Term)

This anti-Indian Hedgehog antibody is a 兔 多克隆 antibody detecting Indian Hedgehog in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 山羊, 马, 兔 和 斑马鱼. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2782160
发货至: 中国

Quick Overview for Indian Hedgehog 抗体 (N-Term) (ABIN2782160)

抗原

See all Indian Hedgehog (IHH) 抗体
Indian Hedgehog (IHH)

适用

人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 山羊, 马, 兔, 斑马鱼

宿主

  • 78
  • 6
  • 4

克隆类型

  • 77
  • 11
多克隆

标记

  • 42
  • 9
  • 7
  • 6
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Indian Hedgehog antibody is un-conjugated

应用范围

  • 58
  • 36
  • 35
  • 16
  • 13
  • 13
  • 12
  • 10
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 10
    • 8
    • 8
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    AAWGCGPGRV VGSRRRPPRK LVPLAYKQFS PNVPEKTLGA SGRYEGKIAR

    预测反应

    Cow: 86%, Dog: 86%, Goat: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against IHH. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human IHH
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 411 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mirza, Qiao, Tateyama, Miyamoto, Xiuli, Seo: "3?-Hydroxysterol-Delta24 reductase plays an important role in long bone growth by protecting chondrocytes from reactive oxygen species." in: Journal of bone and mineral metabolism, Vol. 30, Issue 2, pp. 144-53, (2012) (PubMed).

  • 抗原

    Indian Hedgehog (IHH)

    别名

    IHH

    背景

    IHH is an intercellular signal essential for a variety of patterning events during development. It binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. It is implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones and induces the expression of parathyroid hormone-related protein (PTHRP).
    Alias Symbols: BDA1, HHG2
    Protein Interaction Partner: RHOD, HHIP, PTCH2, PTCH1,
    Protein Size: 411

    分子量

    45 kDa

    基因ID

    3549

    NCBI登录号

    NM_002181, NP_002172

    UniProt

    Q14623

    途径

    Hedgehog Signaling
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