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HBEGF 抗体 (N-Term)

The 兔 多克隆 anti-HBEGF antibody is suitable to detect HBEGF in samples from 人, 小鼠, 大鼠, Cow, Pig, 犬, 豚鼠 和 兔. It has been validated for WB.
产品编号 ABIN2782149
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HBEGF 抗体 (N-Term) (ABIN2782149)

抗原

See all HBEGF 抗体
HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

适用

人, 小鼠, 大鼠, Cow, Pig, 犬, 豚鼠, 兔

宿主

  • 98
  • 19
  • 5
  • 1
兔

克隆类型

  • 91
  • 27
  • 3
多克隆

标记

  • 49
  • 11
  • 9
  • 6
  • 6
  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This HBEGF antibody is un-conjugated

应用范围

  • 48
  • 28
  • 28
  • 26
  • 22
  • 13
  • 10
  • 10
  • 7
  • 6
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 27
    • 15
    • 15
    • 13
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    HBEGF Antibody - N-terminal region

    序列

    FLAAVLSALV TGESLERLRR GLAAGTSNPD PPTVSTDQLL PLGGGRDRKV

    预测反应

    Cow: 100%, Dog: 86%, Guinea Pig: 79%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against HBEGF. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N-terminal region of Human HBEGF
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45201-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

    别名

    HBEGF

    背景

    Background Information: HBEGF is a growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. It is required for normal cardiac valve formation and normal heart function. HBEGF promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. It also acts as a diphtheria toxin receptor.

    Gene Name: heparin-binding EGF-like growth factor

    Alternative Symbols: DTR, DTS, DTSF, HEGFL

    Protein Name: Proheparin-binding EGF-like growth factor

    分子量

    22kDa

    基因ID

    1839

    NCBI登录号

    NP_001936

    UniProt

    Q99075

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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