IL12RB2 抗体 (Middle Region)
Quick Overview for IL12RB2 抗体 (Middle Region) (ABIN2782132)
抗原
See all IL12RB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- DVWYMKRHID YSRQQISLFW KNLSVSEARG KILHYQVTLQ ELTGGKAMTQ
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%, Sheep: 100%
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产品特性
- This is a rabbit polyclonal antibody against IL12RB2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human IL12RB2
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anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (AA 301-400) antibody
IL12RB2 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (AA 1-862) antibodyIL12RB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (AA 105-214) antibodyIL12RB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H6 unconjugated
anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (AA 756-783) antibodyIL12RB2 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (AA 759-788), (C-Term) antibodyIL12RB2 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (AA 559-647) antibodyIL12RB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (AA 285-441) antibodyIL12RB2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (AA 366-470) antibodyIL12RB2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (AA 1-862) antibodyIL12RB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (C-Term) antibodyIL12RB2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))
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别名
- IL12RB2
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背景
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The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.
Protein Interaction Partner: SOCS3, IL12RB2, IL12RB1, STAT4, IL12B, JAK2,
Protein Size: 659 -
分子量
- 72 kDa
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基因ID
- 3595
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途径
- JAK/STAT Signaling
抗原
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