PSMA 抗体 (C-Term)
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北京 101111
Quick Overview for PSMA 抗体 (C-Term) (ABIN2781974)
抗原
See all PSMA (FOLH1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- FOLH1 Antibody - C-terminal region
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序列
- FYRHVIYAPS SHNKYAGESF PGIYDALFDI ESKVDPSKAW GEVKRQIYVA
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against FOLH1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human FOLH1
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anti-Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1) (AA 44-750) antibody
FOLH1 适用: 人, 小鼠, 大鼠, Pig WB, IHC (p), ICC 宿主: 小鼠 Monoclonal GCP-04 unconjugated
anti-Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1) (AA 274-587) antibodyFOLH1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1) (AA 44-177) antibodyFOLH1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2D10E10 unconjugated
anti-Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1) (AA 232-433) antibodyFOLH1 适用: 人, 犬, 马, Cat WB, IHC 宿主: 小鼠 Monoclonal FOLH1-2354 unconjugated
anti-Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1) (AA 44-750) antibodyFOLH1 适用: 人 FACS, IP, ICC, MS 宿主: 小鼠 Monoclonal GCP-05 unconjugated
anti-Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1) (AA 275-588) antibodyFOLH1 适用: Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1) (AA 161-190) antibodyFOLH1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1) (AA 161-190), (N-Term) antibodyFOLH1 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB33647 unconjugated
anti-Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1) antibodyFOLH1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IF 宿主: 小鼠 Monoclonal 2E1 unconjugated
anti-Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1) (AA 1-719) antibodyFOLH1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3B5 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44691-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))
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别名
- FOLH1
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背景
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Background Information: FOLH1 is a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. A mutation in the gene encoding FOLH1 may be associated with impaired intestinal absorption of dietary folates.It is used as an effective diagnostic and prognostic indicator of prostate cancer.This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants.
Gene Name: Folate hydrolase (prostate-specific membrane antigen) 1
Alternative Symbols: PSM, FGCP, FOLH, GCP2, PSMA, mGCP, GCPII, NAALAD1, NAALAdase
Protein Name: Glutamate carboxypeptidase 2
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分子量
- 84kDa
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基因ID
- 2346
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NCBI登录号
- NP_004467
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UniProt
- Q04609
抗原
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