Growth Hormone Receptor 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for Growth Hormone Receptor 抗体 (N-Term) (ABIN2781772)
抗原
See all Growth Hormone Receptor (GHR) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- LQSVNPGLKT NSSKEPKFTK CRSPERETFS CHWTDEVHHG TKNLGPIQLF
-
预测反应
- Human: 100%
-
产品特性
- This is a rabbit polyclonal antibody against GHR. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human GHR
-
-
anti-Growth Hormone Receptor (GHR) (AA 101-200) antibody
GHR 适用: 人, 小鼠, 大鼠, Pig, 绵羊 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 353-588) antibodyGHR 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) antibodyGHR 适用: 人 ELISA, IHC, IF 宿主: 兔 Monoclonal 10C11 unconjugated Recombinant Antibody
anti-Growth Hormone Receptor (GHR) (AA 19-118) antibodyGHR 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3A12 unconjugated
anti-Growth Hormone Receptor (GHR) (AA 315-574) antibodyGHR 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 36-266) antibodyGHR 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (N-Term) antibodyGHR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 19-184) antibodyGHR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 19-118) antibodyGHR 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 36-85) antibodyGHR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 638 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- Growth Hormone Receptor (GHR)
-
别名
- GHR
-
背景
-
GHR is a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature.This gene encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GHBP
Protein Interaction Partner: FBXW11, JAK2, GHR, GH1, BTRC, UBC, SKP1, SOCS2, STUB1, PTPRH, PTPRB, PTPN13, PTPN9, PTPN3, PTPN2, PTPN1, DUSP7, NCOA6, STAT5B, SOCS3, SOCS1, SGTA, CISH, GRB10, STAT5A, AP2A1, SHC1, TYK2, PTPN6, PTPN11, PRLR, PIK3R1, JAK1, IRS1, GH2, GRB2, STAT3, PLCG1,
Protein Size: 638 -
分子量
- 70 kDa
-
基因ID
- 2690
-
NCBI登录号
- NM_000163, NP_000154
-
UniProt
- P10912
-
途径
- NF-kappaB Signaling, JAK/STAT Signaling, Response to Growth Hormone Stimulus
抗原
-
