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Notch1 抗体 (Middle Region)

Name: Notch1 抗体 (Middle Region)
SKU: ABIN2781033
Availability: OutOfStock

This anti-Notch1 antibody is a 兔多克隆 antibody detecting Notch1 in WB. Suitable for 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠和马.

WB Suggested Anti-NOTCH1 Antibody Titration: 0. (Notch1 抗体 (Middle Region))

Host: Rabbit Target Name: NOTCH1 Sample Tissue: Human HT1080 Whole Cell Antibody Dilution: 1ug/ml (Notch1 抗体 (Middle Region))

Rabbit Anti-NOTCH1 Antibody Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue Observed Staining: Plasma membrane Primary Antibody Concentration: 1:100 Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (Notch1 抗体 (Middle Region))

IHC

3 images

产品编号 ABIN2781033

发货至: 中国

Quick Overview for Notch1 抗体 (Middle Region) (ABIN2781033)

抗原

See all Notch1 (NOTCH1) 抗体

Notch1 (NOTCH1) (Notch 1 (NOTCH1))

适用

人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马

宿主

兔

克隆类型

多克隆

标记

This Notch1 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product NOTCH1 Primary Antibody

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Middle Region

序列

EHPFLTPSPE SPDQWSSSSP HSNVSDWSEG VSSPPTSMQS QIARIPEAFK

预测反应

Cow: 79%, Dog: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 79%, Rat: 93%, Zebrafish: 93%

产品特性

This is a rabbit polyclonal antibody against NOTCH1. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human NOTCH1
anti-Notch 1 (NOTCH1) antibody (APC)
NOTCH1 适用: 人, 小鼠 ICFC 宿主: 小鼠 Monoclonal mN1A APC

anti-Notch 1 (NOTCH1) antibody (PE)
NOTCH1 适用: 人, 小鼠 ICFC 宿主: 小鼠 Monoclonal mN1A PE

anti-Notch 1 (NOTCH1) (AA 1919-2079) antibody
NOTCH1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Notch 1 (NOTCH1) (AA 2101-2300) antibody
NOTCH1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Notch 1 (NOTCH1) (Cleaved-Val1754) antibody
NOTCH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Notch 1 (NOTCH1) (AA 20-216) antibody
NOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 unconjugated

anti-Notch 1 (NOTCH1) (AA 20-216) antibody (HRP)
NOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 HRP

anti-Notch 1 (NOTCH1) (AA 20-216) antibody (FITC)
NOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 FITC

anti-Notch 1 (NOTCH1) (AA 20-216) antibody (Biotin)
NOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 Biotin

anti-Notch 1 (NOTCH1) (AA 20-216) antibody (PE)
NOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 PE

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 2555 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

Notch1 (NOTCH1) (Notch 1 (NOTCH1))

别名

NOTCH1

背景

NOTCH1 is a member of the Notch family. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TAN1, hN1
Protein Interaction Partner: USP12, UBC, TGFBR1, WWP1, FBXW7, EGFL7, LATS2, RBPJ, ITCH, NEDD4L, ARRB1, MAML1, Su(H), XIAP, MDM2, CAMK4, NUMB, MCM5, MCM3, SMAD9, LIMK2, IPO5, TNPO1, KPNB1, KIF2A, IFI16, NCKAP1L, HDAC1, HCLS1, HCFC1, GPS1, ERH, DHX15, DHX8, CHD4, CDC27, LRBA, CCT6A, RU
Protein Size: 2555

分子量

88 kDa

基因ID

4851

NCBI登录号

NM_017617, NP_060087

UniProt

P46531

途径

Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development