SIX Homeobox 1 抗体 (N-Term)
Quick Overview for SIX Homeobox 1 抗体 (N-Term) (ABIN2780732)
抗原
See all SIX Homeobox 1 (SIX1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- ERLGRFLWSL PACDHLHKNE SVLKAKAVVA FHRGNFRELY KILESHQFSP
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
-
产品特性
- This is a rabbit polyclonal antibody against Six1. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
-
anti-SIX Homeobox 1 (SIX1) antibody
SIX1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (Middle Region) antibodySIX1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (AA 144-262) antibodySIX1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (AA 69-102) antibodySIX1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53311 unconjugated
anti-SIX Homeobox 1 (SIX1) (C-Term) antibodySIX1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 绵羊, Pig, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (AA 1-284) antibodySIX1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C7 unconjugated
anti-SIX Homeobox 1 (SIX1) (Internal Region) antibodySIX1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (AA 60-270) antibodySIX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (N-Term) antibodySIX1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 284 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- SIX Homeobox 1 (SIX1)
-
别名
- Six1
-
背景
-
Six1 is a transcription factor that is involved in regulation of organogenesis. It seems to be required for development of kidney, muscle and inner ear and to be involved in later steps of myogenic differentiation. It may be involved in limb tendon and ligament development. It binds a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter. It is thought to be regulated by association with Dach and Eya proteins. Six1 acts as activator of the IGFBP5 promoter, probably coactivated by EYA2. Repression of precursor cell proliferation in myoblasts is switched to activation through recruitment of EYA3 phosphatase to the SIX1-DACH1 complex. During myogenesis, Six1 seems to act together with EYA2 and DACH2 .
Alias Symbols: BB138287
Protein Interaction Partner: Eya4, Eya1, Smarca4, Neurog1, Neurod1, Smarcc2, Sox2, Smarcc1, Eya3, Dach1,
Protein Size: 284 -
分子量
- 32 kDa
-
基因ID
- 20471
-
NCBI登录号
- NM_009189, NP_033215
-
UniProt
- Q62231
-
途径
- Sensory Perception of Sound, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
-
