SIX Homeobox 1 抗体 (Internal Region)
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- 抗原 See all SIX Homeobox 1 (SIX1) 抗体
- SIX Homeobox 1 (SIX1)
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIX Homeobox 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- SIX1 Antibody detects endogenous levels of total SIX1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human SIX1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product SIX1 Primary Antibody
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anti-SIX Homeobox 1 (SIX1) antibody
SIX1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) antibodySIX1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal CL0185 unconjugated
anti-SIX Homeobox 1 (SIX1) (Middle Region) antibodySIX1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (AA 144-262) antibodySIX1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (AA 69-102) antibodySIX1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53311 unconjugated
anti-SIX Homeobox 1 (SIX1) (AA 1-284) antibodySIX1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C7 unconjugated
anti-SIX Homeobox 1 (SIX1) (C-Term) antibodySIX1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 绵羊, Pig, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (AA 60-270) antibodySIX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (N-Term) antibodySIX1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, 绵羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- SIX Homeobox 1 (SIX1)
- 别名
- SIX1 (SIX1 产品)
- 别名
- BOS3 antibody, DFNA23 antibody, TIP39 antibody, BB138287 antibody, six1b antibody, six2 antibody, zgc:92332 antibody, XSix1 antibody, six1 antibody, zgc:77345 antibody, SIX homeobox 1 antibody, sine oculis-related homeobox 1 antibody, SIX homeobox 1a antibody, SIX homeobox 1 L homeolog antibody, SIX homeobox 1b antibody, SIX1 antibody, Six1 antibody, six1a antibody, six1.L antibody, six1b antibody
- 背景
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Description: Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development. Plays an important role in the development of several organs, including kidney, muscle and inner ear. Depending on context, functions as transcriptional repressor or activator. Lacks an activation domain, and requires interaction with EYA family members for transcription activation. Mediates nuclear translocation of EYA1 and EYA2. Binds the 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the MYOG promoter. Regulates the expression of numerous genes, including MYC, CCND1 and EZR. Acts as activator of the IGFBP5 promoter, probably coactivated by EYA2. Repression of precursor cell proliferation in myoblasts is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex. During myogenesis, seems to act together with EYA2 and DACH2 (By similarity). Regulates the expression of CCNA1.
Gene: SIX1
- 分子量
- 33 kDa
- 基因ID
- 6495
- UniProt
- Q15475
- 途径
- Sensory Perception of Sound, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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