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SIX Homeobox 1 抗体 (AA 69-102)

SIX1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53311 unconjugated
产品编号 ABIN6244222
发货至: 中国
  • 抗原 See all SIX Homeobox 1 (SIX1) 抗体
    SIX Homeobox 1 (SIX1)
    抗原表位
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 69-102
    适用
    • 29
    • 18
    • 14
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 25
    • 4
    克隆类型
    • 26
    • 3
    多克隆
    标记
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIX Homeobox 1 antibody is un-conjugated
    应用范围
    • 15
    • 13
    • 5
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This SIX1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 69-102 amino acids from the Central region of human SIX1.
    克隆位点
    RB53311
    亚型
    Ig Fraction
    Top Product
    Discover our top product SIX1 Primary Antibody
  • 应用备注
    WB: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    SIX Homeobox 1 (SIX1)
    别名
    SIX1 (SIX1 产品)
    别名
    BOS3 antibody, DFNA23 antibody, TIP39 antibody, BB138287 antibody, six1b antibody, six2 antibody, zgc:92332 antibody, XSix1 antibody, six1 antibody, zgc:77345 antibody, SIX homeobox 1 antibody, sine oculis-related homeobox 1 antibody, SIX homeobox 1a antibody, SIX homeobox 1 L homeolog antibody, SIX homeobox 1b antibody, SIX1 antibody, Six1 antibody, six1a antibody, six1.L antibody, six1b antibody
    背景
    Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development. Plays an important role in the development of several organs, including kidney, muscle and inner ear. Depending on context, functions as transcriptional repressor or activator. Lacks an activation domain, and requires interaction with EYA family members for transcription activation. Mediates nuclear translocation of EYA1 and EYA2. Binds the 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the MYOG promoter. Regulates the expression of numerous genes, including MYC, CCND1 and EZR. Acts as activator of the IGFBP5 promoter, probably coactivated by EYA2. Repression of precursor cell proliferation in myoblasts is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex. During myogenesis, seems to act together with EYA2 and DACH2 (By similarity). Regulates the expression of CCNA1.
    分子量
    32210
    UniProt
    Q15475
    途径
    Sensory Perception of Sound, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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