EZH2 抗体 (N-Term)
Quick Overview for EZH2 抗体 (N-Term) (ABIN2780595)
抗原
See all EZH2 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- N-Term
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                                            序列
- KGPVCWRKRV KSEYMRLRQL KRFRRADEVK SMFSSNRQKI LERTEILNQE
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                                            特异性
- From peptide immunogen, will recognize all 5 isoforms.
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                                            预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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                                            产品特性
- This is a rabbit polyclonal antibody against EZH2. It was validated on Western Blot and immunohistochemistry.
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                                            纯化方法
- Affinity Purified
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                                            免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human EZH2
 
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                                            应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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                                            说明
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                        Antigen size: 751 AA 
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- Lot specific
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                                            缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
- Avoid repeated freeze-thaw cycles.
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                                            储存条件
- -20 °C
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                                            储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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    - EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
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                                            别名
- EZH2
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                                            背景
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                        EZH2 is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems.
 Alias Symbols: ENX1, EZH1, KMT6, WVS2, ENX-1, KMT6A
 Protein Interaction Partner: FBXW11, CEP63, HOTAIR, EED, BRCA1, SUZ12, SNAI1, SRSF1, SDCBP, UPF1, RBBP7, RBBP4, RAP1GAP, PLEC, PKM, POTEE, DHX36, AEBP2, HIST4H4, KLC4, SERPINB12, PHF5A, FIP1L1, FBXL18, CPSF7, DDX3X, DBN1, SLC25A10, COPB1, CALML3, ATP5C1, ATP5B, ATP2A2, ARG1, AR, ANXA
 Protein Size: 751
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                                            分子量
- 85 kDa
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                                            基因ID
- 2146
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                                            NCBI登录号
- NM_001203247, NP_004447
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                                            UniProt
- Q15910
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                                            途径
- Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation
 抗原
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