SSRP1 抗体 (N-Term)
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北京 101111
Quick Overview for SSRP1 抗体 (N-Term) (ABIN2780478)
抗原
See all SSRP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- SSRP1 Antibody - N-terminal region
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序列
- MAETLEFNDV YQEVKGSMND GRLRLSRQGI IFKNSKTGKV DNIQAGELTE
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against SSRP1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SSRP1
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anti-Structure Specific Recognition Protein 1 (SSRP1) (AA 2-381) antibody
SSRP1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodySSRP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodySSRP1 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) (AA 1-300) antibodySSRP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) (Internal Region) antibodySSRP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) (AA 1-242) antibodySSRP1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodySSRP1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB350 unconjugated Recombinant Antibody
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodyKO Validated SSRP1 适用: 人 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodySSRP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) (AA 611-660) antibodySSRP1 适用: 人, 小鼠, 大鼠, 猴, Cow, 豚鼠, Pig, Bat, Drosophila melanogaster, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38249-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))
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别名
- SSRP1
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背景
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Targeted Subunit: SSRP1
Background Information: SSRP1 is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. SSRP1 contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. It also functions as a co-activator of the transcriptional activator p63.The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: Structure specific recognition protein 1
Alternative Symbols: FACT, T160, FACT80
Protein Name: FACT complex subunit SSRP1
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分子量
- 81kDa
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基因ID
- 6749
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NCBI登录号
- NP_003137
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UniProt
- Q08945
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途径
- Chromatin Binding
抗原
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