ERCC3 抗体 (N-Term)
(1 reference)Quick Overview for ERCC3 抗体 (N-Term) (ABIN2780326)
抗原
See all ERCC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MGKRDRADRD KKKSRKRHYE DEEDDEEDAP GNDPQEAVPS AAGKQVDESG
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预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 79%, Human: 100%, Pig: 93%, Rabbit: 79%, Rat: 79%, Yeast: 90%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against ERCC3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ERCC3
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anti-DNA Repair Protein Complementing XP-B Cells (ERCC3) (C-Term) antibody
ERCC3 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DNA Repair Protein Complementing XP-B Cells (ERCC3) (N-Term) antibodyERCC3 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-DNA Repair Protein Complementing XP-B Cells (ERCC3) (AA 242-261) antibodyERCC3 适用: 人 WB, ELISA, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 3G4 unconjugated
anti-DNA Repair Protein Complementing XP-B Cells (ERCC3) (AA 513-782) antibodyERCC3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-DNA Repair Protein Complementing XP-B Cells (ERCC3) (AA 601-700) antibodyERCC3 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-DNA Repair Protein Complementing XP-B Cells (ERCC3) (AA 29-128) antibodyERCC3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-DNA Repair Protein Complementing XP-B Cells (ERCC3) (N-Term) antibodyERCC3 适用: 人, Cow, 犬, 兔, 斑马鱼, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-DNA Repair Protein Complementing XP-B Cells (ERCC3) (AA 512-782) antibodyERCC3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 782 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "A Recurrent ERCC3 Truncating Mutation Confers Moderate Risk for Breast Cancer. ..." in: Cancer discovery, Vol. 6, Issue 11, pp. 1267-1275, (2016) (PubMed).
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: "A Recurrent ERCC3 Truncating Mutation Confers Moderate Risk for Breast Cancer. ..." in: Cancer discovery, Vol. 6, Issue 11, pp. 1267-1275, (2016) (PubMed).
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- ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))
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别名
- ERCC3
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背景
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ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kDa subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription.
Alias Symbols: BTF2, GTF2H, RAD25, TFIIH, XPB
Protein Interaction Partner: XIAP, CEP70, UBC, rev, SRPK2, CDK7, TP53, E2F1, CDK8, CCNC, GTF2H5, ERCC2, MSANTD2, UVSSA, POLR2C, KPNA3, RAD52, MMS19, SIX5, GTF2H4, GTF2H3, GTF2H1, tat, COPS2, GTF2H2, NEDD8, ERCC6, POLR2A, AR, CCNH, MYC, MNAT1, ZSCAN1, ATF7IP, GCN1L1, ERCC5, BCR, PSMC5
Protein Size: 782 -
分子量
- 89 kDa
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基因ID
- 2071
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NCBI登录号
- NM_000122, NP_000113
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UniProt
- P19447
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途径
- DNA Damage Repair
抗原
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