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ERCC3 抗体 (N-Term)

Cited in 1 publication. This anti-ERCC3 antibody is a 兔 多克隆 antibody detecting ERCC3 in WB. Suitable for 人, 大鼠, Cow, 犬, 兔, 斑马鱼, 豚鼠, Pig 和 Saccharomyces cerevisiae.
产品编号 ABIN2780326
发货至: 中国
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Quick Overview for ERCC3 抗体 (N-Term) (ABIN2780326)

抗原

See all ERCC3 抗体
ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

适用

人, 大鼠, Cow, 犬, 兔, 斑马鱼, 豚鼠, Pig, Saccharomyces cerevisiae

宿主

  • 35
  • 8
  • 1
  • 1

克隆类型

  • 38
  • 7
多克隆

标记

  • 24
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This ERCC3 antibody is un-conjugated

应用范围

  • 35
  • 13
  • 13
  • 12
  • 7
  • 7
  • 6
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
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  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    MGKRDRADRD KKKSRKRHYE DEEDDEEDAP GNDPQEAVPS AAGKQVDESG

    预测反应

    Cow: 86%, Dog: 86%, Guinea Pig: 79%, Human: 100%, Pig: 93%, Rabbit: 79%, Rat: 79%, Yeast: 90%, Zebrafish: 79%

    产品特性

    This is a rabbit polyclonal antibody against ERCC3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ERCC3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 782 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Vijai, Topka, Villano, Ravichandran, Maxwell, Maria, Thomas, Gaddam, Lincoln, Kazzaz, Wenz, Carmi, Schrader, Hart, Lipkin, Neuhausen, Walsh, Zhang, Lejbkowicz, Rennert, Stadler, Robson, Weitzel et al.: "A Recurrent ERCC3 Truncating Mutation Confers Moderate Risk for Breast Cancer. ..." in: Cancer discovery, Vol. 6, Issue 11, pp. 1267-1275, (2016) (PubMed).

  • 抗原

    ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

    别名

    ERCC3

    背景

    ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kDa subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription.
    Alias Symbols: BTF2, GTF2H, RAD25, TFIIH, XPB
    Protein Interaction Partner: XIAP, CEP70, UBC, rev, SRPK2, CDK7, TP53, E2F1, CDK8, CCNC, GTF2H5, ERCC2, MSANTD2, UVSSA, POLR2C, KPNA3, RAD52, MMS19, SIX5, GTF2H4, GTF2H3, GTF2H1, tat, COPS2, GTF2H2, NEDD8, ERCC6, POLR2A, AR, CCNH, MYC, MNAT1, ZSCAN1, ATF7IP, GCN1L1, ERCC5, BCR, PSMC5
    Protein Size: 782

    分子量

    89 kDa

    基因ID

    2071

    NCBI登录号

    NM_000122, NP_000113

    UniProt

    P19447

    途径

    DNA Damage Repair
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